Best IMD Podcasts (2025)

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Supply chains: How GenAI has gone from disappointment to game-changer 24:43

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3d ago24:43

24:43

In this episode of Mike and Amit Talk Tech, on the IMD Podcast network, our hosts discuss the transformative role of generative AI in supply chains. Joining the show is Professor Carlos Cordon, an IMD expert with over 30 years of experience in technology and strategy. Cordon reflects on his journey from the world of IT leadership to academia and ex…

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IMD Research Round-Up: Lysosomal Storage Disorders 37:59

8d ago37:59

37:59

Silvia and Rodrigo are joined by Dr Ray Wang, Director of the multidisciplinary Foundation of Caring Lysosomal Storage Disorder Program at the Children's Hospital of Orange County. Silvia asks Dr Wang and Rodrigo (who also happens to be a researcher in this field) about cutting-edge advances in LSD research: from base editing in Pompe disease and p…

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Penetrance, expressivity, and outcomes in classic galactosemia 26:57

1d ago26:57

26:57

In this episode we discuss new insights into the variability of long-term outcomes in classic galactosemia. Joining me are Nikki Smith, Olivia Garrett, and Judy Fridovich-Keil, who together explore how complications in cognitive, motor, and speech domains emerge, cluster, and vary in severity across patients. Their study highlights both patterns an…

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Leaner, cleaner, faster, stronger: How ABB is reshaping an engineering icon for the future 41:39

14d ago41:39

41:39

In this episode of the CEO Dialogue series, Jean-François Manzoni speaks with Morten Wierod, President and CEO of ABB, about how one of the world’s great engineering companies is transforming itself for the road ahead. With 110,000 employees, 170 factories, and more than $30 billion in annual revenues, ABB has long been central to electrification, …

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From wake-up call to global coalition: How Maersk is pushing shipping toward net zero 42:22

14d ago42:22

42:22

How Maersk is rewriting the rules of shipping decarbonization – through collaboration, purpose, and placing big bets on the fuels of the future. What happens when one of the world’s largest shipping companies decides not to wait for regulation – but to lead by collaboration? In this episode of Leaders Unplugged, IMD President David Bach sits down w…

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GenAI and healthcare with Achim Plueckebaum 23:15

16d ago23:15

23:15

On the IMD Podcast network, Mike Wade and Amit Joshi speak about the future of health, with Achim Plueckebaum, a contributor to their latest book GAIN. As a senior executive with decades of experience in the life sciences industry, Plueckebaum believes AI will have a transformative impact on medicine, pharmacology, and patient care. He emphasizes t…

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Adenosine Kinase 23:40

16d ago23:40

23:40

What if one enzyme could link metabolism, epigenetics, and therapy across conditions as diverse as epilepsy, cancer, and inflammation?In this episode, we dive into the fascinating world of adenosine kinase (ADK), an ancient enzyme that controls adenosine levels, energy balance, and even DNA methylation. Dr Detlev Boison join us to discuss their rec…

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Footprints of IMD: Movement Disorders... with Dakota Peacock and Darius Ebrahimi-Fakhari 20:37

25d ago20:37

20:37

The first updated Footprints article requires two guests to do it justice - Dr Dakota Peacock and Dr Darius Ebrahimi-Fakhari join Eva Morava to discuss movement disorders in Inherited Metabolic Disease.Read the referenced paper here: https://doi.org/10.1016/j.ymgme.2025.109084Find IMDs associated with psychiatric presentations at: https://www.iemba…

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Uncertainty and Enterprise: Amar Bhidé on Risk, Imagination, and Innovation 34:45

24d ago34:45

34:45

IMD Dean of Faculty and Research Stefan Michel sits down with Amar Bhidé - Emeritus Professor at Tufts University, and a founding member of the Center on Capitalism and Society at Columbia. Drawing on insights from his latest book, Uncertainty and Enterprise: Venturing Beyond the Known, Amar unpacks the vital difference between risk and uncertainty…

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Metabolic mysteries: Incidental adrenal calcifications in a neonate 5:55

1M ago5:55

5:55

A newborn with no symptoms, an unexpected X-ray finding, and a puzzle that points in many possible directions. Follow Dr. Tolulope Tolufase as he unpacks a neonatal case where incidental adrenal calcifications conceal a far deeper mystery.Read the full report here: https://doi.org/10.1136/bcr-2025-265278…

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How Hindustan Unilever is winning over India’s middle class 45:47

1M ago45:47

45:47

In this I by IMD podcast, Rohit Jawa, the former CEO of Hindustan Unilever, outlines how he is reshaping the company’s strategy to meet the evolving needs of India’s growing middle class, leveraging digital transformation, talent development, and a future-focused growth agenda. In conversation with IMD’s Jean-François Manzoni, Jawa explains how he …

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The treatment landscape in CDG 31:13

1M ago31:13

31:13

In this episode, we speak with Irena Muffels and Eva Morava about their recent review, The Therapeutic Future for Congenital Disorders of Glycosylation. We explore the three pillars they propose for advancing CDG treatment: improving disease models, enhancing clinical trial readiness, and finding scalable strategies that move us beyond one-gene-at-…

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How to bounce back after summer, with Michael Watkins and Brenda Steinberg 37:26

1M ago37:26

37:26

In this I by IMD podcast, host Michael Watkins, Professor of Leadership and Organizational Change, sits down with executive coach Brenda Steinberg to discuss a common challenge: the "post-summer blues." They reframe this experience not as a slump but as a transition and discuss the importance of acknowledging and processing the seasonal change. For…

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The future of Edge AI, with Tomoko Yokoi 13:20

2M ago13:20

13:20

In this episode of Mike and Amit Talk Tech from the IMD Podcast Network, hosts Mike Wade and Amit Joshi speak with Tomoko Yokoi, Senior Researcher at IMD, about one of AI’s fastest-growing frontiers — Edge AI. Drawing on over 20 years of experience in B2B and B2C industries, Tomoko explains what Edge AI is, why it matters, and how it could reshape …

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IMD Research Round-Up: Newborn Screening 45:14

2M ago45:14

45:14

In this episode, Prof Chris Vorster (Director, Centre for Human Metabolomics, North-West University, South Africa), Sarah Viall (Assistant Professor, Molecular and Medical Genetics, Oregon Health & Science University, USA) and PD Dr. med. Ulrike Mütze (Consultant, Heidelberg University Hospital, Germany) join Silvia Radenkovic and Rodrigo Starosta …

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“It’s time for a complete reset” – Maria Vassalou on the future of investing 32:45

2M ago32:45

32:45

Global rules are being rewritten. Pictet’s Maria Vassalou joins David Bach to discuss BRICS, AI, aging societies – and why leaders must rethink everything they thought they knew. As global trade rules unravel, AI accelerates, and demographics shift dramatically, what should business leaders do? What do they need to rethink, and where should they in…

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ARS1 Deficiencies 20:55

2M ago20:55

20:55

In this episode, Sabine Fuchs and Eva Hoytema discuss their recent work exploring the expanding clinical spectrum of aminoacyl-tRNA synthetase deficiencies, highlighting diagnostic challenges and emerging insights into this complex group of rare disorders.Setting the Stage for Treatment of Aminoacyl-tRNA Synthetase (ARS)1-Deficiencies: Phenotypic C…

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The 100 year life, with Andrew Sharman and Lynda Gratton 34:19

2M ago34:19

34:19

What it means to be “working-age” is changing, and so too are the ways in which people look at their careers. The traditional “three-stage” life is giving way to a “multi-stage” life, and businesses that fail to adapt to this new reality are in danger of being left behind. In this special episode of the IMD Podcast Network, we bring together two of…

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Shortcast: Investigating the utility of leukocyte sialic acid measurements in Lysosomal FSASD 4:22

2M ago4:22

4:22

Marya Sabir shares new insights into the utility of leukocyte sialic acid levels as a diagnostic and monitoring tool in free sialic acid storage disorder.Investigating the Utility of Leukocyte Sialic Acid Measurements in Lysosomal Free Sialic Acid Storage DisorderMarya S. Sabir, et alhttps://doi.org/10.1002/jmd2.70029…

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How Mars CEO Poul Weihrauch is future-proofing the legacy of one of the world’s largest family-owned companies 46:07

2M ago46:07

46:07

Poul Weihrauch explains how family ownership gives him the opportunity to prioritize purpose alongside profit. In an era where CEOs are under relentless pressure to deliver short-term gains while also addressing long-term challenges like sustainability, Poul Weihrauch considers himself fortunate. As the CEO of Mars – the 114-year-old, family-owned …

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Why Democracies Die – and What Business Leaders Must Do 1:04:20

2M ago1:04:20

1:04:20

Harvard’s Daniel Ziblatt explores how democracies fail and why business leaders must act now before it’s too late. “Democracy is a system of competition: not harmony, but contest... When that competition is fair, something extraordinary happens.” In this gripping keynote and fireside conversation with IMD President David Bach, Harvard professor and…

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Diagnostic delay in Metachromatic Leukodystrophy 21:31

2M ago21:31

21:31

Dr Laura Adang returns to the podcast, this time discussing diagnostic delays in early onset forms of metachromatic leukodystrophy and explains why the only logical route to prompt diagnosis is newborn screening and how gene therapy might lead to a 'normal' life for children, if only we can find them early enough.Characterizing Diagnostic Delays in…

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Is AI good or bad for sustainability? 26:01

2M ago26:01

26:01

AI is a double-edged sword for the environment. Its growth requires masses of energy, water, and rare earth metals. The LLMs of tomorrow may even require the world to bring old power plants, powered by fossil fuels, back online. On the other hand, AI has the potential to accelerate sustainable transformation by providing innovative approaches to en…

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Is AI good or bad for sustainability? 26:01

2M ago26:01

26:01

AI is a double-edged sword for the environment. Its growth requires masses of energy, water, and rare earth metals. The LLMs of tomorrow may even require the world to bring old power plants, powered by fossil fuels, back online. On the other hand, AI has the potential to accelerate sustainable transformation by providing innovative approaches to en…

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IMD Research Round-Up: Glycogen Storage Disorders 32:51

2M ago32:51

32:51

In this episode, Dr Joost Groen, a clinical biochemist at the University Medical Center Groningen, and Dr Matt Gentry, Professor & Chair of Biochemistry & Molecular Biology in the College of Medicine at University of Florida, join Rodrigo and Silvia to discuss new insights, AI, cancer metabolism and some of their favourite papers on Glycogen Storag…

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First-time CEO pitfalls, and how to avoid them 32:49

3M ago32:49

32:49

What got you here won’t get you there. But that’s not all, says Kevin O’Brien, CEO of Gammon Construction in conversation with Professor Ric Roi. You’re also going to need to really unpack the detail of your new brief, marshal the data to spot the opportunities, figure out how to unlock future potential, and bring everyone with you on the journey.…

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“We were so scared of our IPO”: Leaders Unplugged with former On-CEO Marc Maurer 42:15

3M ago42:15

42:15

Marc Maurer didn’t build ON by playing it safe. In this live conversation with IMD’s Alyson Meister, the outgoing Co-CEO explains why betting on purpose, rejecting hype, and ignoring the industry playbook paid off: 1. Culture over hype. “We’re actually the anti-metaverse.” ON doubled down on real-life movement instead of pixels, and built a brand w…

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Future therapies in galactosemia 33:35

3M ago33:35

33:35

In this latest episode, we explore what's next for treating classic galactosemia. The discussion is anchored in two fascinating recent publications, including the wide-angle perspective from “Reshaping the Treatment Landscape of a Galactose Metabolism Disorder” and a deep dive into something delightfully unexpected: purple sweet potato color (PSPC)…

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Halfway 2025: How to read two quarters under Trump 2.0 27:50

3M ago27:50

27:50

Richard Baldwin delves into the Trump administration, and what to glean from months of economic madness. Looking ahead, Richard discussed how trade and tariffs will directly impact businesses, from small enterprises to large corporations, and what business leaders can do to mitigate risk potential regional variations and sector-specific impacts.…

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Metabolic mysteries: GI bleeding, gallbladder polyps and evolving developmental delay 8:25

3M ago8:25

8:25

Dr JP Stevens shares the mystery of a 5-year-old boy presenting with severe gastrointestinal bleeding and cholestasis. Inpatient investigation reveals gallbladder polyps and, on assessment after recovery he is found to have signs of developmental delay. Can you recognise the clues in the presentation?https://onlinelibrary.wiley.com/doi/10.1097/PG9.…

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Why do the biggest headlines go to the worst leaders? Howard Yu and Martin Gutmann 40:24

3M ago40:24

40:24

Historian-turned-business-professor Martin Gutmann talks to IMD’s Howard Yu about busting the “hero” myth, how Churchill really won WWII, and the silent strategist who conquered both poles while the flashy explorers froze. Along the way he reveals humility as the ultimate power-skill and hands leaders a playbook for quietly, predictably winning.…

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Speech and Language in Batten disease 23:34

3M ago23:34

23:34

Lottie Morison joins the podcast to discuss recent insights around speech and language progression and assessment in CLN2 and CLN3 disease. Lottie is the first speech and language pathologist to lead an episode and brilliant exemplifies the multidisciplinary nature of IMD care. Speech, Language and Non-verbal Communication in CLN2 and CLN3 Batten D…

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Metabolic Minds 2025 23:41

3M ago23:41

23:41

A special episode of the podcast as we visit the presentation day for the Metbionet Metabolic Minds leadership programme to hear about a plan to safeguard the future of specialist biochemistry services in the UK. Dr Rachel Carling explains the programme and then we hear from three of the course candidates, Dr Alana Burns, Annabel Wong and Freya Has…

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IMD Research Round-Up: Redox metabolism 35:46

3M ago35:46

35:46

Dr Luciana Hannibal, Research Group Leader / Head of Translational Metabolomics at the Centre for Integrative Biological Signalling Studies in Freiburg, and Dr Julien Park, a Physician-scientist at the Children's University Hospital Münster, are Rodrigo and Silvia's latest guests, providing a thorough overview of disorders of Redox Metabolism. Auth…

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In an age of grievance, find every opportunity to listen - Cynthia Hansen and Richard Edelman 20:12

4M ago20:12

20:12

Richard Edelman, CEO of the communications firm Edelman, explores in a conversation with Cynthia Hansen, Managing Director of Adecco Group’s Innovation Foundation, why so many people are dissatisfied with authority and institutions.By IMD

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ECHS1 deficiency and valine restriction 14:42

4M ago14:42

14:42

Dr Travis Johnson and Dr Sarah Mele join the podcast to explain why flies make great models for Short-chain enoyl-CoA hydratase 1 deficiency (ECHS1D) and how their work is shedding light on different treatment modalities.Valine Restriction Extends Survival in a Drosophila Model of Short-Chain Enoyl-CoA Hydratase 1 (ECHS1) DeficiencySarah Mele, et a…

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Metabolic mysteries: A child with episodic seizures and multiple diagnoses 5:21

4M ago5:21

5:21

Dr Mrinmayee Takle and Dr Kuntal Sen discuss the challenging dilemma of a child, presenting from infancy with recurrent seizures and three different (wrong) diagnoses including opsoclonus-myoclonus-ataxia syndrome.Read the article: https://doi.org/10.1002/cns3.20098Mrinmayee Takle, Dhwani Sahjwani, Diana Bharucha-Goebel, Tyler Rapp, Cecilia Bouska,…

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From the classroom to the boardroom – why do IMD alumni lead differently? 26:29

4M ago26:29

26:29

Three alumni. Three decades. One question: What makes IMD’s leadership journey so lasting? What do a former Olympic basketball player, a Japanese strategist in London, and a Swiss energy executive have in common? IMD. In this special MBA reunion episode of Leaders Unplugged, IMD President David Bach welcomes - John Hatch (MBA 1990) - Kazumi Nakayam…

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Managing Metabolic Emergencies - Intoxication type disorders 26:35

4M ago26:35

26:35

Treatment is available for most intoxication-type disorders, but would you know what to do in an emergency. In this podcast, Dr Dexter Tarr discusses the acute management when these conditions cause encephalopathy, seizures, stroke-like episodes, thromboses, liver failure, cardiac failure, arrhythmias and rhabdomyolysis. Emergency Management of Int…

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IEMs in Adult Metabolic Centres: 10 Years Later 22:50

4M ago22:50

22:50

Michel Tchan and Mirjam Langeveld join the podcast to look at changes to adult IMD services over the last decade and consider the challenge to develop services to meet the needs of growing patient numbers over the next 10 years.The Frequencies of Different Inborn Errors of Metabolism in Adult Metabolic Centres: 10 Years Later, Another Report From t…

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How do deans lead when the world turns upside down? 38:28

4M ago38:28

38:28

Global deans on leading through turbulence — and why optimism, not certainty, is the real power in today’s business education. In today’s episode, IMD President David Bach discusses how the rapid global shifts of the moment impact leadership education, with two of his peers: – Catherine Duggan, Dean of the University of Cape Town Graduate School of…

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IMD Research Round-Up: Methylmalonic Aciduria 34:17

5M ago34:17

34:17

Dr Sabine Fuchs, Professor of Metabolic diseases and innovative therapies at the UMC Utrecht, and Dr Sean Froese, a Principal Investigator in the Metabolism Division at University Children’s Hospital Zürich, join Rodrigo and Silvia to discuss new insights and some of their favourite papers on Methylmalonic Aciduria. Authors opinions are their own a…

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Shortcast: Sleep quality in children with hepatic GSDs, a prospective observational pilot study 8:38

5M ago8:38

8:38

Lucas Agnoletto and Dr Rebecca Halligan report work looking at sleep quality in children with hepatic GSDs, considering whether sleep is impacted by poor glycemic control or our efforts to improve this through overnight feeding.Sleep quality in children with hepatic glycogen storage diseases, a prospective observational pilot studyLucas Agnoletto, …

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David Bach: Why we all benefit from America’s top universities 35:45

5M ago35:45

35:45

In the latest episode, IMD President David Bach explains the vital importance of the partnership between the US government and the elite research universities, what we can learn from the vibrancy of the Middle East, and why Ted Lasso is a better leadership role model than Elon Musk. “The US built its global edge by attracting the world’s best. Now,…

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NAXD deficiency 32:57

5M ago32:57

32:57

Dr Carole Linster and Dr Nicole van Bergen explain why metabolism isn't perfect and how disorders of enzyme repair present their own challenges. In an episode that explores Niacin and longevity, we also hear why NAXD deficiency is an important differential in acute cardiomyopathy and provides an aetiology that could be highly amenable to treatment.…

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Imaging readiness in the gene therapy era 22:54

5M ago22:54

22:54

Asthik Biswas, Spyros Batzios, and Kshitij Mankad expand on their recent letter to the editor to explain why ushering in the new era of gene therapy treatments requires not just clinical but also imaging readiness. Imaging readiness in the gene therapy era-exploring standardized protocols for response assessmentAsthik Biswas, et alhttps://doi.org/1…

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Episode 3: David Bach with Stuart DeCew and Geraldine Matchett 38:23

5M ago38:23

38:23

Welcome to the third episode of Leaders Unplugged, presented by IMD, and hosted by IMD's president David Bach, together with Remote Daily's founder Felix Zeltner. Leaders Unplugged is real talk with the impactful – candid, honest, and fresh from behind the scenes. Today, we take you behind the scenes of a recent gathering led by the World Business …

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IMD Research Round-Up: Congenital Disorders of Glycosylation 39:58

5M ago39:58

39:58

Dr Matthew Wilson, Postdoctoral Fellow at the Centre for Human Genetics, KU Leuven, joins hosts Silvia Radenkovic and Rodrigo Starosta to discuss a scintillating selection of CDG papers in our first ever research round-up. Authors opinions are their own and do not represent their institutions.The papers discussed include:A pseudoautosomal glycosyla…

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Exploring the disease burden in Arginase 1 deficiency 27:51

6M ago27:51

27:51

It's an Arg1 extravaganza as Reena Sharma, Sara Olofsson, Karolina Stepien and Alison Woodall discuss three separate papers looking at the Salford Royal experience of a cohort of adults with Arginase 1 deficiency and the wider health and societal cost of the condition. Retrospective analysis of arginase 1 deficiency progression in adults over 5 yea…

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The Interview: Jim Pulcrano speaks with Ruchita Sinha of AV8 Ventures 17:54

6M ago17:54

17:54

This interview with Ruchita Sinha, partner at AV8 Ventures, explores her journey from science to venture capital and her approach to early-stage investing. She discusses AV8’s focus on AI-driven innovation in healthcare, enterprise tech, and financial services, and shares insights on evaluating founders, what distinguishes a good company builder, n…