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Let's Talk ID

Infectious Diseases Society of America (IDSA)

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Let's Talk ID is a podcast by the Infectious Diseases Society of America, featuring discussions with experts on a range of topics related to infectious diseases including antimicrobial resistance, ID diagnostics and outbreaks such as COVID-19, Ebola and measles. Episodes on IDSA’s guidelines are also available.*The views and opinions expressed in this podcast are those of the speakers and do not necessarily reflect the views or positions of the Infectious Diseases Society of America.
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Clinical microbiology explained in simple terms, suitable for students and microbiologists alike. We discuss organisms, reactions, infectious diseases, and more. Hosted by Luis Plaza, a Medical Laboratory Scientist and microbiologist, who also shares his experiences in the field.
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The PIDS Podcast

Pediatric Infectious Diseases Society

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Welcome to the PIDS Podcast! The PIDS Podcast is an information hub from the Pediatric Infectious Diseases Society featuring discussions with experts on a range of topics (eg, clinical guidelines, treatment recommendations, diagnostics) related to childhood infectious diseases. Tune in to hear from experts in the field!
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Enterprise Security Tech presents The Cyber Jack Podcast. The Cyber Jack Podcast brings together critical news, expert insights, and product information to help CISOs, CIOs, and CEOs make informed IT technology and cybersecurity decisions.
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Insights to innovation. Together we dig in with industrial designers, professors, business leaders, and entrepreneurs to extract the hidden tips, techniques, and mind-states that drive the act of creating sustainably. If you love Design, this is the place to be. If you acknowledge the challenges ahead for humanity and want to make a difference, you are in the right place. If you are infinitely curious about the world around you and love stumbling upon morsels of inspiration, this is the plac ...
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The Infectious Diseases Society of America (IDSA) has released new guidelines for the treatment of complicated urinary tract infections. In this episode, we break down the key updates: Changes to the definition of complicated UTIs The role of newer antibiotic agents How and when to use antibiograms A four-step framework for guiding therapy When car…
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Bloodstream infections can progress rapidly to sepsis—bringing high costs, high mortality, and lasting effects. In the second episode of this series in collaboration with bioMérieux, Luis speaks with Dr. Jeff Cies, Senior Medical Advisor at bioMérieux, about how molecular diagnostics are reshaping bloodstream infection diagnosis. They discuss: Limi…
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Brucella is a familiar name in the lab—but recent updates to the sentinel guidelines are reshaping how we approach this pathogen. In this episode, I’m joined by Dr. Laura Filkins and Dr. Paige Larkin to discuss the latest changes: updates in nomenclature, the removal of certain Brucella species from the select agent list, and the renewed emphasis o…
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Antimicrobial resistance (AMR) continues to grow as a global health threat, making infections harder to treat and leaving fewer options for patients. The need for new antibiotics is an urgent matter — but traditional discovery methods are slow and limited. In this episode of Let’s Talk Micro, Luis is joined by Dr. James Collins, professor at MIT an…
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Last week, we discussed early growth isolates for antimicrobial susceptibility testing (AST) and the importance of obtaining results sooner. This week, we revisit an earlier study that looked at early growth but using disk diffusion. In this episode, I was joined by Dr. Carey-Ann Burnham, Dr. Daniel Webber, and Meghan Wallace to discuss their work.…
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In this episode of Let’s Talk Micro, Dr. Jennifer Dien Bard and Dr. Lucas Osborn discuss their recent study on early growth antimicrobial susceptibility testing (AST). Traditional AST often requires 18–24 hours of incubation of isolates, delaying targeted treatment. Their research shows that using 6-hour early growth isolates with both automated an…
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Anna Person, MD, FIDSA, discusses the role of street medicine in improving access to HIV services and opportunities to support SM programs under Medicaid with Nathan Nolan, MD, MPH, MPHE, Founder of Street Medicine STL and Chris Menschner, Director, Complex Care Programs at the Center for Health Care Strategies. Shape the future of ID with peers fr…
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Bruce Gellin, MD, MPH, FIDSA, ID physician and senior advisor at the Georgetown University Global Health Institute, joins Buddy Creech, MD, MPH, FPIDS, to discuss the Vaccine Integrity Project and the importance of ensuring vaccine policy remains grounded in evidence. The two explore strategies for countering misinformation, building public trust, …
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This week, Luis is joined by Dr. Ashlan Kunz-Coyne to discuss some of the newest antibiotics for urinary tract infections (UTIs). They explore why extended-spectrum beta-lactamases (ESBLs) are a growing concern, the impact of E. coli sequence type 131, and where new agents like cefepime–enmetazobactam, sulopenem, and tebipenem fit into treatment. T…
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Season 5 premieres today! Antimicrobial susceptibility testing (AST) is essential for guiding effective treatment—but how has it evolved, and what challenges are we still facing? In the first episode of this series in collaboration with bioMérieux, Dr. Andrea Prinzi joins Let’s Talk Micro to explore the evolution of AST—from early methods to modern…
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This episode of Let’s Talk Micro features Dr. Andrea Prinzi, a clinical microbiologist and frequent contributor to the American Society for Microbiology. Andrea joins the podcast to discuss a critical topic in clinical microbiology: antimicrobial susceptibility testing and breakpoints. Are labs using outdated breakpoints—and what does that mean for…
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The Clinical Microbiology Procedures Handbook (CMPH) has long been a trusted resource for laboratories. With the release of its 5th edition, this essential reference continues to guide clinical microbiologists through evolving standards, methods, and best practices. In this episode, Luis is joined by the editors‑in‑chief, Dr. Amy Leber and Dr. Care…
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This week, Luis is joined by Dr. Christopher Doern from VCU Health to explore the complex world of diabetic wound cultures. How does diabetes impair wound healing—and what makes these infections so difficult to diagnose and treat? Dr. Doern dives into the microbiology behind diabetic foot wounds, highlighting the impact of bacterial diversity, spec…
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Recorded live at ASM Microbe 2025, this episode captures the energy of the American Society for Microbiology’s annual event. Luis shares his top takeaways from the conference floor—including standout poster presentations, emerging technologies, and trending topics in microbiology. One clear theme dominated this year: rapid diagnostics for identific…
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In this episode of Let’s Talk Micro, we dive into the fast-paced world of rapid antimicrobial susceptibility testing (AST). Recorded live from ASM Microbe 2025, Luis is joined by Dr. Carey-Ann Burnham, CEO of Pattern Bioscience and Editor-in-Chief of the ASM Case Reports journal. Together, they explore how innovative technologies—like single-cell m…
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Judy Guzman-Cottrill, DO, Professor of Pediatrics at Oregon Health & Science University, and John Brooks, MD, former CDC medical officer, rejoin Mati Hlatshwayo Davis, MD, MPH, FIDSA, to discuss the impact of federal funding cuts, including the return of preventable diseases, the loss of mental health resources, and what can be done to protect the …
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How familiar are you with partnerships and collaborations between the laboratory and the diagnostics industry? In this episode Luis is joined by Dr. Andrea Prinzi and Dr. Kristen Smith to explore how partnerships between clinical labs, public health institutions, and the diagnostics industry drive innovation in in-vitro diagnostics (IVDs). What is …
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TBT- This week Let's Talk Micro is talking about virology, specifically about the Human Immunodeficiency Virus (HIV). This episode features an interview with Dr. Hsu, a stem cell specialist from the Weill Medical College at Cornell University in New York. She discusses an article about a patient that has been possibly cured from HIV after a stem ce…
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In this two-part series, Judy Guzman-Cottrill, DO, Professor of Pediatrics, Division of Infectious Diseases at Oregon Health and Science University, and John Brooks, MD, former CDC medical officer and epidemiologist, join Mati Hlatshwayo Davis, MD, MPH, FIDSA, to discuss the real-time consequences of federal funding cuts on public health. From dism…
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This week Luis is joined by Dr. Callan Bleick and Dr. Mohammed Al Musawa to talk about an antibiotic that was recently approved by the Food and Drug Administration (FDA): aztreonam-avibactam. Our guests wrote a review about this drug and they joined the podcast to talk about it. What is aztreonam? What is avibactam? Why combine them? What type of a…
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There are many challenges when it comes to outbreak detection. It involves surveillance, time, and effort among other factors. Some of these challenges are linking multiple patients to an outbreak, or investigating a potential outbreak that turns out to be separate occurrences of an infection. In this episode Luis is joined by Dr. Alex Sundermann t…
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ID physicians Priya Nori, MD, FSHEA, FIDSA, and Gonzalo Bearman, MD, MPH, FACP, FSHEA, FIDSA, join Paul Sax, MD, FIDSA, to discuss challenges often faced by ID specialists, including gaslighting and uncompensated labor. The three discuss how physicians can advocate for themselves, set boundaries, and push for meaningful change within their institut…
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This week Luis continues going over Haemophilus. This time he goes over biochemicals, testing systems, and susceptibility testing. What is the ALA test? What commercial systems are able to identify Haemophilus? What about for Haemophilus influenzae? What is HTM agar? Are there any vaccines for H. influenzae? Tune in to find out more. More informati…
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In this episode Luis continues going over organisms. This time he goes over the genus Haemophilus. We start with an overview of the different species of Haemophilus. Why can’t Haemophilus grow on blood agar? What are the X and V factors? Satellite phenomenon? What is the gram stain? What about media? Tune in for the first part of a series about Hae…
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If you are part of the clinical microbiology community, you might have heard of a CPEP Fellowship, or might have met someone pursuing one. In this episode Luis is joined by Dr. Samuel Goodfellow to talk about the Subcommittee on Postgraduate Educational Programs (CPEP) Fellowship. Dr. Goodfellow is currently participating in one and he joins us to …
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Infectious diseases fellow Sam Peterson, MD, shares her unique journey to ID with Buddy Creech, MD, MPH, FPIDS. The two explore the power of mentorship, the value of storytelling, and what it takes to inspire the next generation of ID specialists.By Infectious Diseases Society of America (IDSA)
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What led or inspired you to choose the field of microbiology or laboratory medicine? Has your profession changed within the field? In this series where microbiologists and people from laboratory medicine talk about their careers, Luis is joined by Dr. Andrea Prinzi and Lisa Parlich. Andrea is a microbiologist that works in the industry and the co-h…
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Discovery of new potential antimicrobial compounds is important as we take many measures to combat antimicrobial resistance (AMR). In this episode Luis is joined by Dr. Manoj Jangra and Dr. Dmitrii Travin to discuss lariocidin: a potential antibiotic. What is the mechanism of action? What are lasso peptides? Tune in to listen about the discovery of…
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There are many challenges in the microbiology laboratory. As a leader, you have to deal with things like validations, verifications, and knowledge of regulations among other things. As a microbiologist in a non-leadership position you need to be familiar with some of these as well. With so much information out there, where do we go? In this episode…
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John Fangman, MD, discusses threats to the Affordable Care Act and how they could impact people with HIV with JoAnn Volk, MA, research professor, founder, and co-director of the Center on Health Insurance Reforms at Georgetown University’s McCourt School of Public Policy and Tim Horn, Director, Medication Access at NASTAD.…
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Paul Sax, MD, FIDSA, is joined by infectious diseases physicians and international medical graduates, Vidya Sundareshan, MD, and Alfredo Mena Lora, MD, FIDSA, to discuss how international medical graduates (IMGs) can pursue a career in infectious diseases. The trio discuss visa options, job search strategies, and how political change could impact t…
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The field of Microbiology continues to change. Organisms were primarily identified in the clinical laboratory by biochemical testing. Then MALDI-TOF came to the lab and was incorporated into the workflow. Now labs are bringing next-generation sequencing (NGS). What is NGS? How does it work? Have you heard of Nanopore technologies? In this episode D…
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Is your laboratory accredited by the College of American Pathologists (CAP) ? Are you familiar with their checklists? What are the latest updates to the microbiology checklist? In this episode Luis is joined by Dr. Christi Wojewoda to discuss the latest updates to the microbiology checklist: media quality control and nomenclature. Why are some medi…
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Paul Sax, MD, FIDSA, speaks with Adam Ratner, MD, MPH, Professor of Pediatrics and Microbiology at NYU Grossman School of Medicine and Director of the Division of Pediatric Infectious Diseases at Hassenfeld Children’s Hospital and Bellevue Hospital Center, about his book, "Booster Shots: The Urgent Lessons of Measles" and the rise of vaccine preven…
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The latest edition of the CLSI M100 has been published. What are the latest updates? One of them is the deletion of breakpoints for Burkholderia cepacia complex. What are the recommendations for susceptibility testing? Dr. April Bobenchik returns to the podcast to talk to Luis about the latest updates. She also talks about the M45. Will there be an…
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Anna Person, MD discusses threats to the Medicaid program and how they could impact people with HIV with Kate McManus, MD, MSc, FIDSA, Associate Professor of Medicine at the University of Virginia in the Division of Infectious Diseases and International Health and Amy Killelea, JD, Assistant Research Professor at the Georgetown University Center on…
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This week Luis continues going over organisms. This time he goes over Eikenella. Are there any other Eikenella species other than Eikenella corrodens? What is the morphology of E. corrodens? How about biochemicals? What are the members of the HACEK group? What is the HACEK group known for? Tune in to learn about this organism, which is seen in infe…
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Talk about a great career! In this episode Luis is joined by Janet Hindler. Janet is a microbiologist with a career that has spanned over many decades. Just like most Medical Laboratory Scientists, she started working in the lab and early on she had a passion for microbiology. Then she got involved in work that took her beyond the bench such as the…
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IDSA Board Member Mati Hlatshwayo Davis, MD, MPH, FIDSA, discusses public health forecasting and response efforts with Lior Rennert, PhD, director of the Center for Public Health Modeling and Response at Clemson University, and Dylan George, PhD, director of CDC’s Center for Forecasting and Outbreak Analytics (CFA).…
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