Best Functioning Tumor Podcasts (2025)

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Neurobiology of Aging Lecture #3: mTOR, Functional and Structural Alterations, and Biomarkers 1:19:09

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28m ago1:19:09

1:19:09

NOTE: This lecture with slides presented can be found on the Brain Ponderings YouTube Channel. This episode begins by highlighting recent evidence showing adverse effects on the brain of excessive activation of the mTOR pathway as a consequence of dietary branched chain amino acid consumption. Then I describe evidence that Beyond the age of 40 year…

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Neurobiology of Aging Lecture 2: Cellular and Molecular Hallmarks of Brain Aging 1:21:19

39m ago1:21:19

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NOTE: This lecture with slides presented can be found on the Brain Ponderings YouTube Channel. This video describes 12 major changes that occur in brain cells during aging and their involvement in decline in brain function and the development of neurodegenerative disorders including dementia and Parkinson's disease.…

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Neurobiology of Aging Lecture Series: #1 – Theories, Comparative Biology, and Animal Models of Aging 1:21:18

7h ago1:21:18

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NOTE: This lecture with slides presented can be found on the Brain Ponderings YouTube Channel. This is the first of five lectures on the Neurobiology of Aging. The other four lectures cover cellular hallmarks, structural and functional aspects, biomarkers, how neurodegenerative disorders occur during aging, and how aging can be slowed and brain hea…

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Norm Haughey: Membrane Sphingomyelin and Ceramides Abnormalities in Alzheimer's and Other Diseases 55:32

3d ago55:32

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The lipid membrane bilayer of cells is composed of fats including phospholipids, cholesterol, and sphingomyelin. Enzymes called sphingomyelinases can cleave sphingomyelin resulting in the liberation of ceramides which can diffuse within the cell and act as signaling molecules. In this episode I talk with Tulane University Professor Norm Haughey abo…

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"Spotlight on Pharmacists" with Amanda Cass, PharmD, BCPS, BCOP 54:46

6d ago54:46

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ABOUT THIS EPISODE Who is a pharmacist, and how are they involved in the care of neuroendocrine cancer patients? In this episode, Dr. Amanda Cass, a clinical pharmacist in the Thoracic Oncology Clinic at Vanderbilt Medical Center, explains the unique role pharmacists play—why they’re sometimes called “doctor,” how they support patients starting tre…

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"Understanding Carcinoid Syndrome & GLP-1 Drugs in Neuroendocrine Tumors" with Dr. Joseph Dillon 1:09:02

13d ago1:09:02

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ABOUT THIS EPISODE Carcinoid syndrome can be confusing and often difficult to diagnose. In this episode, Dr. Joseph Dillon, Endocrinologist and Director of the University of Iowa Neuroendocrine Multidisciplinary Tumor Clinic, explains what carcinoid syndrome is, how it’s diagnosed, and the various ways it can be treated. He highlights key symptoms,…

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David Gutmann – Cancer Neuroscience and the Sociobiology of Brain Tumors 59:27

18d ago59:27

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Brain tumor cells interact with neurons, glial cells, and immune cells in complex ways that often benefit the cancer cells while compromising the function of normal neural cells. In this episode I talk with Washington University Neurology Professor David Gutmann about brain cancer cells and their communication with surrounding normal cells. A major…

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Ray Dorsey: Environmental Toxins and Parkinson's Disease – Evidence and What to Avoid 57:26

28d ago57:26

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There is considerable evidence that exposure to certain chemicals in the environment cause Parkinson's disease in many people. In this episode neurologist Ray Dorsey talks about some of the chemicals that may cause Parkinson's disease including the pesticides paraquat and rotenone, and trichloroethylene and perchloroethylene which are chemicals use…

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Ai Yamamoto: "ALFY" Cleanses Neurons of Pathological Proteins to Counteract Degenerative Diseases 1:12:11

1M ago1:12:11

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A shared feature of neurodegenerative disorders is accumulation of aggregated proteins within neurons: Tau in Alzheimer's disease; alpha-synuclein in Parkinson's disease; huntingtin in Huntington's disease; and TDP43 in amyotrophic lateral sclerosis. In this episode Ai Yamamoto – an Associate Professor Neurology at Columbia University – talks about…

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Radiotherapy induced neurocognitive decline 16:05

1M ago16:05

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Description: Dr. Iyad Alnahhas interviews Dr. Charlotte Sleurs about her and her team's recent manuscript entitled: "Radiotherapy-induced neurocognitive decline among adult intracranial tumor patients: A voxel-based approach", published online in Neuro-Oncology in May 2025.By Drs. Iyad Alnahha and Charlotte Sleurs

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Marco Capogrosso – Spinal Cord Stimulation for Recovery of Function After Stroke or Trauma 1:03:16

2M ago1:03:16

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Remarkable advances are being made in the development and clinical applications of stimulation devices that enable recovery of motor function in patients who have suffered a spinal cord injury, a stroke, and even those with rare disabling genetic disorders. At the forefront of this research is Marco Capogrosso at the University of Pittsburgh. He ha…

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Young Women & Breast Cancer: Understanding Early-Onset Risk, Genetics & Fertility 19:48

2M ago19:48

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In this episode of Baptist Health’s Doc-to-Doc, we take a closer look at one of the most concerning trends in oncology — the rise of breast cancer among younger women. Dr. Anastasia Tousimis, Deputy Director of Baptist Health Cancer Care, sits down with Dr. Louise Morrell, Chief Medical Executive of Lynn Cancer Institute, to discuss what’s driving …

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Scott Ayton: Iron, Brain Health, Parkinson's and Alzheimer's Diseases – A Delicate Balance 1:15:26

2M ago1:15:26

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Dietary iron is essential for health as it plays important roles in the ability of hemoglobin to carry oxygen throughout the body and brain. In addition, iron is involved in various functions in cells including the generation of ATP in mitochondria and DNA synthesis. The vast majority of iron is bound to proteins such as ferritin and heme. However,…

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"NEN Treatments: Focus On DLL3" with Dr. Rohit Thummalapalli 55:51

2M ago55:51

55:51

By Neuroendocrine Cancer Foundation

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"Spotlight on Endocrinology" with Dr. Run Yu 58:31

2M ago58:31

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By Neuroendocrine Cancer Foundation

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The Pituitary Playbook — Functional Tumors, Vision Risk & Endoscopic Solutions 21:18

2M ago21:18

21:18

In this Baptist Health Doc-to-Doc episode, Dr. Michael McDermott, Chief Medical Executive of Baptist Health Miami Neuroscience Institute sits down with Dr. Evan Bander, Neurosurgeon & Co-Director of the Pituitary Tumor Program at the Baptist Health Miami Neuroscience Institue, to unpack the complexities of the body’s “master gland.” Together, they …

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The New Arrhythmia Playbook—Hybrid Ablation, LAA Management & AI 30:27

3M ago30:27

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In this episode of Baptist Health's Doc-to-Doc, we explore the evolving landscape of arrhythmia care with host Tom Nguyen, M.D., Chief Medical Executive of Baptist Health Heart & Vascular Care, Director of Minimally Invasive Surgery, and Barry T. Katzen Endowed Chair at Miami Cardiac & Vascular Institute, and Professor and Chair of the Department o…

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QOL and cognitive functioning in patients with oligodendroglioma 18:22

3M ago18:22

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Dr. Iyad Alnahhas interviews Drs. Florien Boele and Martin Klein about their recent manuscript entitled: "Health-related quality of life and cognitive functioning in survivors of oligodendroglioma: An international cross-sectional investigation", published online in Neuro-Oncology in July 2025.By Drs. Iyad Alnahhas, Florien Boele, Martin Klein

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Erik Musiek: Brain Cell Circadian Clock Proteins in Neuroplasticity, Aging, and Alzheimer's Disease 1:12:00

2M ago1:12:00

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Health depends upon proper regulation of circadian rhythms of cell and organ functions. Disruption of circadian rhythms has detrimental consequences for brain function and resilience and abnormal circadian rhythms are a common feature of Alzheimer's disease. In this episode neurology professor Erik Musiek talks about the roles of specific circadian…

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The Field of Blood Cancers: How Have We Evolved 14:54

3M ago14:54

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In this episode of Doc to Doc, we explore groundbreaking advances in the treatment of blood cancers with two of the field’s leading experts: Dr. Guenther Koehne, Deputy Director and Chief of Blood and Marrow Transplant, Hematologic Oncology and Benign Hematology, and Dr. Firas El Chaer, Chief of Leukemia Services and Medical Director of Infusion — …

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Reframing Thyroid Cancer: Precision, Progress & Personalized Care 22:37

3M ago22:37

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Why do thyroid cancers demand a more nuanced approach, despite high survival rates? In this episode of Doc to Doc, Dr. Meghan Crawley, head and neck surgical oncologist at Miami Cancer Institute, joins Dr. Rachel Slotcavage, endocrine surgeon at Lynn Cancer Institute, to explore what makes thyroid cancers so unique and how treatment approaches are …

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Post-operative radiation in recurrent grade 1 meningiomas 19:39

3M ago19:39

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Dr. Iyad Alnahhas interviews Drs. Felix Sahm and Maximilian Deng about their recent manuscript entitled: "Postoperative radiotherapy in subtotally-resected recurrent WHO grade 1 meningiomas with intermediate/ high-risk molecular profiles", published online in Neuro-Oncology in May 2025.By Drs. Felix Sahm, Maximilian Deng, Iyad Alnahhas

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Georgia Hodes: Sex Differences in Responses to Stress and Vulnerability to Neurological Disorders 1:11:08

3M ago1:11:08

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Chronic uncontrolled stress is a risk factor for many different diseases including mental and neurodegenerative disorders. The effects of such stress on the brain differ considerably between females and males. However, the vast majority of preclinical studies in animal models have included only males which in some cases has resulted in therapeutic …

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Advancing the Standard: Gynecologic Cancer Care 28:58

3M ago28:58

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What happens when landmark trials challenge long-standing surgical standards? In this episode of Doc to Doc, Dr. Thomas Morrissey, director of gynecologic oncology at Lynn Cancer Institute, joins Dr. Ryan Kahn, gynecologic oncologist at Miami Cancer Institute, to explore how data from pivotal studies like TRUST, SHAPE, and MIRASOL are redefining tr…

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Marian Joëls and Ron de Kloet: How the Brain Responds to Stress in Health and Mental Disorders 1:14:54

3M ago1:14:54

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In stressful situations the brain communicates with the adrenal glands stimulating them to release adrenaline and cortisol. This stress responsive neuroendocrine system plays important adaptive roles by regulating energy metabolism, attention, and learning and memory. However, without a recovery period chronic uncontrolled stress such as psychosoci…

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mRNA CAR T against GD2 in high-grade glioma models 29:43

3M ago29:43

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Dr. Maya Graham interviews Dr. Jessica Foster about her and her team's recent manuscript, entitled "Transient mRNA CAR T cells targeting GD2 provide dose-adjusted efficacy against diffuse midline glioma and high-grade glioma models". This work was published online in Neuro-Oncology in May 2025.By Drs Maya Graham, Jessica Foster, Iyad Alnahhas

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Josh Helman: Multipronged Approaches for Preventing and Treating Alzheimer's Dementia 59:38

4M ago59:38

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Clearly demonstrated as being effective for cardiovascular disease, lifestyle medicine is becoming an important discipline for the prevention and treatment of age-related brain disorders including Alzheimer's and Parkinson's diseases. In this episode I talk with Dr. Josh Helman about his experience working with patients at lifestyle medicine center…

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Grace (Beth) Stutzmann: Pivotal Role for Calcium in Brain Aging and Alzheimer's Disease 53:14

4M ago53:14

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The calcium ion controls neuronal network activity, synapse function and synaptic plasticity, and is a fundamental mediator of learning and memory. With aging and much more so in Alzheimer's disease the ability of neurons to properly regulate their intracellular calcium levels becomes compromised. Evidence from human and laboratory animal studies h…

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Andrew Dillin – Stress and Aging: Mitochondria are Hubs of Information Flow in and Between Cells 49:00

4M ago49:00

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Long believed to function only as the cell's powerhouse research is revealing that mitochondria actively control a cell's response to various types of stress. Even more amazingly mitochondria send stress-related signals between cells. In this episode UC Berkeley Professor Andy Dillin has made major advances in understanding basic mechanisms of agin…

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Marc Freeman – How Astrocytes Control Neural Circuits in Brain Development, Plasticity, and Disease 1:18:41

4M ago1:18:41

1:18:41

While neurons and the circuits the form have been the major focus of brain research the human brain contains at least as many cells that are not neurons of which astrocytes are by far the most abundant. During the past decade there have been numerous studies that reveal novel and very active roles for astrocytes in regulating the growth of neurons,…

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Polina Shichkova: Metabolic and Biophysical Modeling of Breakdown and Repair of the Aging Brain 1:03:05

5M ago1:03:05

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Because neurons in the brain are electrically excitable and active 24/7 the brain consumes relatively large amounts of energy and must adapt to varying demands on its neural networks. The cellular and molecular complexity of the brain presents a major challenge for understanding not only its second-by-second function but also how neural networks ar…

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"Spotlight on Advanced Practice Providers (NPs & PAs)" with Tiffany Valone 37:46

5M ago37:46

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ABOUT THIS EPISODE Neuroendocrine cancer care typically involves a multidisciplinary team which sometimes involves an Advanced Practice Provider (APP). In this episode, Moffitt Physician Assistant Tiffany Valone clarifies the role of an APP in neuroendocrine cancer. TOP TEN QUESTIONS What is a NP/PA/APP? -Are you a doctor? How are you different fro…

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Corinde Wiers: The Potential of Ketone-Based Interventions for the Treatment of Addiction 1:07:26

5M ago1:07:26

1:07:26

Research on substance use disorders has largely focused on understanding the key neural circuits and neurotransmitter systems that are altered, and on behavioral and pharmacological interventions. However, emerging research findings suggest that alcohol use disorder (AUD) is associated with alterations in energy metabolism and can accelerate brain …

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A transcriptomic atlas of CNS tumors 35:22

5M ago35:22

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Dr. Evan Noch interviews Dr. Akshitkumar Mistry about his and his team's recent manuscript entitled "A clinically annotated transcriptomic atlas of nervous system tumors", published online in Neuro-Oncology in May 2025 Link to the paper: https://academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noaf130/8151442…

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Henning Fenselau – Neural Circuits Controlling Appetite and Energy Metabolism and GLP-1 Actions 56:52

5M ago56:52

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Appetite (hunger and satiety) is controlled by neural circuits in the brain – particularly in the hypothalamus – and their reciprocal connections to peripheral organs involved in energy metabolism (gut and liver). Understanding the structural organization of these circuits (their synaptic connections) and their neurochemistry (particularly which ne…

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Tessa Montague: Disappearing Act - How the Brain Controls Camouflage in Cuttlefish and Octopuses 1:09:01

5M ago1:09:01

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One of the most remarkable feats of biological 'wizardry' in the animal kingdom is the ability of some cephalopods (octopuses, squids, and cuttlefish) to rapidly change the color, patterning, and texture of their skin so as to blend in with their background. They accomplish these feats through the linking of neural circuits in the visual system and…

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Episode 45: "Spotlight on Medical Oncology" with Sandy Kotiah, MD 52:09

5M ago52:09

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One of the key aspects of one’s neuroendocrine cancer care is building your medical team, which typically includes a medical oncologist. In this episode, Medical Oncologist Dr. Sandy Kotiah from Mercy Medical Center in Baltimore expounds on the role of a medical oncologist. She sheds light on the first appointment, communication, and care coordinat…

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Cracking the Code: Genetics in Modern Oncology 28:04

6M ago28:04

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What happens when we stop gatekeeping genetic testing and offer it universally? In this episode of Doc to Doc, Dr. Arelis Martir Negron, medical geneticist at Miami Cancer Institute, joins Dr. Venkatappa to explore how the field of cancer genetics is transforming — and what every clinician should know. From BRCA1 and BRCA2 to multi-gene panels and …

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Gut microbiome in primary CNS lymphoma 15:04

6M ago15:04

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Dr. Iyad Alnahhas interviews Drs. Isaias Hernandez-Verdin and Agusti Alentorn about their recent manuscript entitled: "Gut microbiome modulates the outcome in primary central nervous system lymphoma patients undergoing chemotherapy: An ancillary study from the BLOCAGE trial", published online in Neuro-Oncology in March 2025 Link: https://academic.o…

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Jonathan Long: Lactate-Phe and Ketone-Phe: Exerkines and Fastokines for Brain Health and Plasticity? 1:02:26

6M ago1:02:26

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During vigorous exercise lactic acid (lactate) levels increase in the blood and during fasting and extended exercise the levels of the ketone BHB (b-hydroxybutyrate) increase. In this episode I talk with Stanford University professor Jonathan Long about his recent discovery that lactate and BHB in the blood are bound to the amino acid phenylalanine…

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"Understanding Clinical Trials & How They Fit in the Neuroendocrine Cancer Journey" with Dr. Alexandria Phan 40:38

6M ago40:38

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When in one’s neuroendocrine cancer journey might a clinical trial be considered? What factors influence treatment decisions, including whether to pursue a clinical trial? Dr. Alexandria Phan, medical oncologist at the Medical College of Wisconsin, offers thoughtful guidance on when and how clinical trials fit into the neuroendocrine cancer journey…

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Carlos Matute: Brain White Matter in Health, Endurance Exercise, and Disease 1:17:20

6M ago1:17:20

1:17:20

White matter consists of bundles of long axons that convey information between neural circuits between different brain regions within and between brain hemispheres. These long axons are wrapped with many layers of lipid-rich membranes of oligodendrocytes (a type of glial cell) and it is this 'insulation' that enables rapid propagation of signals ov…

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Michael Kreutz: Amazing Nanomachines in Synapses that Keep Brains Healthy and Wise 1:01:28

6M ago1:01:28

1:01:28

Michael Kreutz is Head of the Neuroplasticity Research Group at the Leibniz Institute for Neurobiology in Magdeburg Germany. Using powerful high resolution microscopy and molecular biology tools his laboratory has shown that autophagy occurs within synapses. Synaptic autophagy is stimulated by neural network activity and is critical for their maint…

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Germline analysis of diffuse midline glioma 29:55

6M ago29:55

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Dr. Evan Noch interviews Dr. Marion Mateos about her and her team's recent manuscript entitled: "Germline analysis of an international cohort of pediatric diffuse midline glioma patients", published online in Neuro-Oncology in March 2025.By Drs. Evan Noch, Marion Mateos, Iyad Alnahhas

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Jordan Grafman: Neural Circuits of Religiosity: 'The Kingdom of God' is in the Prefrontal Cortex 1:11:17

6M ago1:11:17

1:11:17

Belief in supernatural agents and other religious myths arose as a means of 'explaining' the unknown and as a tool for social cohesion and hierarchical control of civilizations. Their religiosity is major feature of a 'believers' self identity as well as their group identity. Compelling evidence from multiple types of studies have revealed the neur…

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Evolving Advances in Brain Tumor Care: Insights from Medical and Radiation Oncology 18:31

6M ago18:31

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Brain tumors remain among the most complex and challenging conditions we confront. There are over 120 histologically distinct tumor types, with survival outcomes varying drastically depending on molecular profile and location. As a result, the need for nuanced, multidisciplinary care has never been more evident. While advances in neuroimaging, geno…

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Sridevi Sarma: Using DSM and Neuro-engineering to Diagnose and Treat Neurological Disorders 52:43

7M ago52:43

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Neurological disorders involve aberrant neural network activity. New technologies are needed for establishing at a fine spatial and temporal resolution the nature of the altered network activity – and for restoring activity to or towards a healthy state. Professor Sri Sarma is an electrical engineer and neuroscientist who is at the forefront of thi…

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Richard Johnson: How High Fructose Intake Induces Obesity and Chronic Diseases of the Body and Brain 1:09:28

7M ago1:09:28

1:09:28

Compelling evidence shows that consumption of high fructose corn syrup in soft drinks and ultraprocessed foods has contributed to the increases in obesity, diabetes, fatty liver disease, and dementia that has occurred during the past 50 years. Professor Richard Johnson's research has been at the forefront of establishing how fructose adversely affe…

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The proteomic landscape of diffuse midline glioma 16:55

7M ago16:55

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Dr. Iyad Alnahhas interviews Drs. Cynthia Hawkins and Arun Vadivel about their recent manuscript entitled: "The proteomic landscape of diffuse midline glioma highlights the therapeutic potential of non-histone protein methyltransferases", published online in Neuro-Oncology in February 2025. More Information…

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Brian Kennedy: Decoding Metabolic Aging Clocks to Understand and Counteract Aging 1:20:19

7M ago1:20:19

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Major progress has recently been made in understanding the aging process at the molecular, cellular, and organ system levels. This knowledge is now being applied in preventative and interventional health care. Moreover, because of the severe burden of age-related diseases on societies governments are increasingly developing strategies to extend hea…