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Focused Ultrasound Foundation Podcasts

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Curing with Sound

Focused Ultrasound Foundation

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Imagine harnessing the power of sound waves to heal the human body–this isn’t science fiction, it’s the reality of focused ultrasound technology. Join the conversation that explores the transformative power of this noninvasive therapy revolutionizing the treatment of nearly 180 diseases and medical conditions and giving hope to patients worldwide. Presented by the Focused Ultrasound Foundation.
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Business Trip

Greg Kubin & Matias Serebrinsky

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Business Trip explores the frontiers of brain and mental health. Each episode features founders, investors, and researchers in psychedelics, neurotechnology, neurometabolism, precision medicine, digital therapeutics, novel modalities, and more.
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Welcome to BIOTECH NATION !!! With understandable interviews requiring no background in science, BTN attracts a wide global audience. From everyday people looking for hope in treatments in development, to bioentrepreneurs interested in the experience of their fellow travelers, to venture capitalists looking for possibilities in cutting-edge breakthroughs, to scientists simply interested in the work of others, BioTech Nation is the voice of human endeavor, driving science to new realities for ...
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This week on Biotech Nation, Paul Hastings, CEO of Nkarta and former chair of BIO—the Biotechnology Innovation Organization—discusses the impact of cuts to research funding and stepping away from recommending vaccines—what this means for you and the biotech industry.By Moira Gunn
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In this episode of Curing with Sound, we speak with Patrick Hope, Executive Director of AdvaMed's Medical Imaging Division, about the critical but often unseen world of medical technology policy and advocacy that makes innovative treatments like focused ultrasound accessible to patients. Patrick shares how AdvaMed, an advocacy organization for the …
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This week on BioTech Nation, Dr. Mark Kendall, CEO of WearOptimo, tells us about progress with their new wearable. You could be dehydrated and not even know it … And exactly how hydrated are you right now, anyway? The old “if you’re thirsty, drink something” turns out to be a little too late.By Moira Gunn
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In this episode of Curing with Sound, we explore how focused ultrasound is being studied as a treatment for depression and anxiety, told through the perspectives of both a leading researcher and a veteran who experienced it firsthand. Noah Philip, MD, is a professor of psychiatry and human behavior at Brown University's Alpert Medical School and a …
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This week on BioTech Nation, Dr. Steve Harr, CEO of Sana Biotechnology, talks about their progress in Type I diabetics, in particular. The New England Journal of Medicine publishes early success with Sana Biotechnology's engineered insulin-producing cells without immunosuppressant drugs.By Moira Gunn
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Greg and Matias interview Brendon Boot of Skin2Neuron. Brendon is a neurologist at Harvard and Mayo Clinic with prior experience as Medical Director at Biogen overseeing their Phase 1b Alzheimer’s trials. In this episode, we discuss: How skin-derived cells can be turned into neurons to repair the brain. Why replacing lost neurons may succeed where …
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This week on BioTech Nation, Dr. Neal Kassell, founder of the Focused Ultrasound Foundation, introduces us to a powerful, non-invasive technology that’s already changing lives, and it doesn’t involve surgery, injections, or pills.By Moira Gunn
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This week on BioTech Nation, Dr. Raza Bokhari, CEO of Medicus Pharma, shares a new non-surgical treatment approach for basal cell carcinoma, the most common form of skin cancer. Their novel microneedle patch delivers a powerful cancer drug directly into the skin, avoiding the scarring, cost, and discomfort of Mohs surgery. With promising phase 2 tr…
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In this episode of Curing with Sound, we speak with Bill Traynor, a Canadian adventurer whose life shifted dramatically when he was diagnosed with ALS (Lou Gehrig's disease), a neurodegenerative disorder with an average life expectancy of just two to five years. Once enjoying high-impact activities like skydiving, race car driving, and scuba diving…
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This week on BioTech Nation, Dr. Eric Topol returns to continue his conversation on, "Super Agers … An Evidenced-Based Approach to Longevity", his evidence-based approach to living longer, healthier lives. He shares why longevity must be accessible to everyone, not just the wealthy, and how new tools like AI, personalized diagnostics, and even gut …
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This week on BioTech Nation, Dr. Eric Topol, professor and Executive Vice President at Scripps Research and author of "Super Agers … An Evidenced-Based Approach to Longevity", breaks down what science really says about aging well and what is just marketing. From immune-boosting cell therapy to the myth of magic longevity pills, Dr. Topol explains h…
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This week on Biotech Nation, Dr. Neil Kumar, founder and CEO of BridgeBio Pharma. Dr. Kumar emphasizes that genetic diseases, particularly Mendelian diseases caused by single gene mutations, are solvable due to advancements in genetic measurement and understanding. He discusses BridgeBio Pharma's innovative corporate structure, which consists of mu…
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Greg and Matias interview Natalie Yivgi-Ohana of Minovia. Natalie is a life science entrepreneur with twenty years’ experience in mitochondrial research and received her PhD in Biochemistry at The Hebrew University in 2007, after which she performed her postdoctoral fellowship at the Weizmann Institute of Science until 2010. In this episode, we dis…
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In this episode of Curing with Sound, we speak with Rosie Xing, PhD, Managing Director of Global Planning, International Marketing, and Business at Chongqing Haifu Medical Technology, a world leader in noninvasive focused ultrasound systems. Founded in 1999 by Professor Zhibiao Wang, Chongqing Haifu has revolutionized treatment for patients across …
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Dr. John Scarlett, President and CEO of Geron Corporation talks about their drug Imetelstat for myelodysplastic syndrome (MDS). MDS patients often require frequent blood transfusions, impacting their quality of life. Imetelstat, a telomerase inhibitor, aims to reduce transfusion dependence by targeting cancer cells in the bone marrow. Phase three t…
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In this episode of Curing with Sound, we hear the remarkable story of Monica Russell, who has lived with severe obsessive-compulsive disorder (OCD) for nearly 30 years. Diagnosed at age nine, Monica pursued a wide range of conventional and alternative treatments before participating in a focused ultrasound clinical trial at Sunnybrook Hospital in T…
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This week on BioTech Nation, Robert Blum, CEO of CytoKinetics, joins me to talk about the company’s decades-long mission to keep hearts beating stronger and longer. With one heart drug under FDA review and more in the pipeline, CytoKinetics is working to address the full spectrum of heart failure, from weak hearts to overactive ones, and even explo…
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Matias and Greg interview Ying-Hui Fu, PhD, is a Professor of Neurology at UCSF and a world leader in the genetics of sleep. Her lab has discovered the first-known genes behind “natural short sleepers”. Her work bridges human genetics and neuroscience to uncover how to modulate sleep for brain health, aging, and neurodegenerative diseases. In this …
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This week on BioTech Nation, BioSTEM Technologies CEO Jason Matuszewski explains how donated placental tissue is being used to treat chronic wounds that just won’t heal, from diabetic ulcers to pressure sores. With millions affected and traditional care often falling short, BioSTEM’s approach offers a new way to support healing and reduce scarring.…
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In this episode of Curing with Sound, we speak with Shiro Horisawa, MD, Director of Stereotactic and Functional Neurosurgery at Tokyo Women's Medical University, who discusses innovative applications of focused ultrasound technology for treating dystonia and other movement disorders. Dr. Horisawa shares insights from his extensive clinical experien…
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This week on BioTech Nation, Biotech Entrepreneur, Dr. Jake Glanville, Founder, Chair and CEO of Centivax, gives us the insider’s view of this Biotech Breakthrough – from the first telephone call through each significant step, all leading to the first breakthrough generalized antivenom vaccine in 125 years.…
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This week on BioTech Nation, Dr. Daniel Kraft, Tech Nation Health Chief Correspondent, returns with highlights from the 2025 NextMed Health conference. From AI-powered health agents to voice-based disease detection, hear what’s emerging at the intersection of medicine, technology, and global health equity.…
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Dr. Peter DeMuth, Chief Scientific Officer of Elicio Therapeutics, discusses the revolutionary approach of detecting cancer at its earliest stages through circulating tumor DNA (ctDNA) tests. Highlighting their innovative treatment method, which aims to train the body's immune cells to recognize and destroy cancer cells, the episode explores the po…
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According to the American Cancer Society, approximately one in eight men will be diagnosed with a prostate condition during their lifetime. Focused ultrasound offers a noninvasive, radiation-free treatment option for prostate conditions and has been approved in more than 50 countries, including the United States. In this episode of Curing with Soun…
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In this episode of Curing with Sound, we speak with Eli Vlaisavljevich, PhD, an Associate Professor in the Department of Biomedical Engineering at Virginia Tech and a renowned innovator in histotripsy, the first completely noninvasive and nonthermal ablation method for treating cancer. The conversation explores histotripsy's expanding applications …
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This week on BioTech Nation, Dr. Cory Nicholas, CEO of Neurona Therapeutics, returns for part two. With early results now in from Neurona’s first clinical trial, patients with severe epilepsy are seeing dramatic improvements, including seizure reductions of over 90 percent, and even full remission in some cases. This one-time treatment delivers new…
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This week on BioTech Nation, Dr. Cory Nicholas, Co-Founder and CEO of Neurona Therapeutics, discusses their groundbreaking success in treating drug-resistant epilepsy. With a single, targeted delivery of lab-grown brain cells, Neurona is offering not just symptom control but the possibility of long-term seizure relief. This is Part 1 of a two-part …
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In this episode of Curing with Sound, we hear from Paul Sayer, a prostate cancer survivor from the United Kingdom, whose life was transformed by focused ultrasound treatment. Diagnosed with aggressive prostate cancer in 2018 and initially advised to undergo surgery, Paul took the initiative to research alternative treatments. His search led him to …
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This week on BioTech Nation, we explore a new approach to cancer treatment that could help patients manage pain without compromising their care. Dr. Lorin Johnson, CSO of Glycyx Therapeutics explains how a new once-daily pill could help patients manage pain without blocking their treatment.By Moira Gunn
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This week on BioTech Nation, Sameer Sabir, CEO of Brixton Biosciences, shares how their breakthrough injectable cold therapy, Neural Ice, could offer lasting relief for osteoarthritis pain. With a drug-free, nerve-targeting approach currently in clinical trials, this innovation may change how we treat joint pain without pills or repeated steroid in…
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In this episode of Curing with Sound, James Mahoney, PhD, associate professor and neuropsychologist at West Virginia University, discusses the use of focused ultrasound for addiction treatment. Dr. Mahoney and the team at the Rockefeller Neuroscience Institute are using neuromodulation to target the nucleus accumbens - the brain's reward center - t…
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This week on BioTech Nation, Luminary Therapeutics CEO Jeff Liter shares how his team is working to make advanced cell therapy easier to access and more affordable. Instead of using each patient’s own cells, they use healthy donor cells that are ready to go. This approach could help more people get treated for cancer and autoimmune diseases like lu…
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Matias and Greg interview Justin Mares, co-founder of TrueMed and Kettle & Fire on current US healthcare and how startups have the opportunity to change the system. In this episode, we discuss: How the US system profits from chronic illness Fixing the food system, environmental toxins, pharma incentives & more Opportunities for founders building in…
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This week on BioTech Nation, Sean Ainsworth, CEO of ImmuSoft, explains how modifying the body’s own B cells to produce therapeutic proteins could revolutionize drug delivery. From improving treatment for rare diseases like Hurler syndrome to potentially replacing injections for autoimmune and metabolic conditions, this new approach opens the door t…
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This week on BioTech Nation, Dr. Thomas Chen, Director of Neuro-Oncology at USC and Founder of NeOnc Technologies, shares treating glioblastoma by delivering a drug directly to the brain through nasal inhalation changes the drug delivery game, bypassing the blood-brain barrier. This technique is achieving results in clinical trials.…
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In this episode of Curing with Sound, Zhen Xu, PhD, the Li Ka Shing Endowed Professor of Biomedical Engineering at the University of Michigan, discusses histotripsy. Dr. Xu and her colleagues developed histotripsy, the first noninvasive, nonthermal ultrasound ablation technique that received FDA approval for liver tumor treatment in 2023. Her work …
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This week on BioTech Nation, I speak with Dr. John Cumbers, founder and CEO of SynBioBeta, the annual synthetic biology conference. We discuss how biology, AI, and technology are transforming industries, covering tracks on human health, planetary health, and hyperscale biology. SynBioBeta 2025 will take place in San Jose, CA, from May 5 to 8.…
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This week on BioTech Nation, Ossium Health co-founder and CEO Kevin Caldwell shares how their breakthrough approach is changing bone marrow transplants. By cryobanking marrow from organ donors, Ossium is reducing wait times, improving access, and preparing for future emergencies. With support from BARDA and promising clinical trial results, this ne…
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This week on BioTech Nation, we explore what happens when your immune system overreacts. Professor Niels Riedemann, CEO of InflaRx, explains how the body’s defense system can sometimes cause more harm than good, leading to serious conditions like rheumatoid arthritis, severe COVID-19, and lung failure. Learn how InflaRx is developing treatments to …
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In honor of Essential Tremor Awareness month, this episode of Curing with Sound, features Michael Werner, a healthcare attorney, who has lived with essential tremor most of his life. After years of struggling with increasingly debilitating tremors that affected daily activities like eating and cooking, he chose to have a noninvasive focused ultraso…
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This week on BioTech Nation, Dr. Daniel Kraft explores how smarter design can make healthcare easier, less stressful, and more effective. From hospitals built for patient comfort to medical apps that adapt to your needs, the way we experience healthcare is evolving. Learn how design thinking and empathy are shaping the future of medicine.…
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This week on BioTech Nation, Catalyst Pharmaceuticals CEO Rich Daly discusses the complexities of treating epilepsy and rare diseases. From the challenges of polypharmacy—where patients need multiple drugs to manage a single condition—to the hurdles of diagnosing and treating ultra-rare diseases.By Moira Gunn
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This episode of Curing with Sound features Elisa Konofagou, PhD, the Robert and Margaret Hariri Professor of Biomedical Engineering and professor of radiology at Columbia University, who is a pioneer and leading expert in focused ultrasound. Dr. Konofagou discusses her important research using focused ultrasound to open the blood-brain barrier, the…
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This week on Biotech Nation, Dr. Ari Azhir, Founder and CEO of Neuvivo, shares the incredible journey of an ALS drug that was once abandoned, but is now making its way toward FDA approval. After two failed phase two trials, the drug was left behind until Dr. Azhir and her team discovered a crucial mistake in the trial data. Now with new insights an…
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Matias and Greg sit down with Brooks Leitner, the newest venture partner at PsyMed Ventures, to explore the future of brain and mental health investing. Brooks, an MD/PhD with deep experience from Yale and the NIH, shares his insights on how a human-first approach is reshaping neuroscience innovation and venture investing. In this episode, we discu…
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This week on BioTech Nation, Dr. Daniel Kraft explores the discovery of "dark" proteins, thousands of previously unknown proteins in the human body. Scientists believe these hidden proteins could be the key to detecting diseases earlier and developing new treatments.By Moira Gunn
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In this episode of Curing with Sound, we talk with Suzanne LeBlang, MD, a neuroradiologist and Director of Clinical Relationships at the Focused Ultrasound Foundation, who offers unique insights into how this technology is reshaping the future of medicine. She shares her experience as an early adopter of focused ultrasound following its FDA approva…
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This week on Biotech Nation, Dr. Lincoln Nadauld shares how Culmination Bio is using 9 million preserved tissue samples and decades of patient data to improve how we understand and treat diseases. From discovering patterns in cancer treatments to exploring breakthroughs in heart and autoimmune diseases, this unique approach is changing medicine.…
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This week on Biotech Nation, Dr. Daniel Kraft discusses why mobility is emerging as a key indicator of health, just like heart rate or blood pressure. From wearable tech that tracks your gait to AI-powered exoskeletons and brain-computer interfaces, new innovations are transforming how we measure and maintain movement.…
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