Best Expertcommentary Podcasts (2025)

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SMuRF-less: CV Prevention Beyond Traditional Risk Factors 24:06

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2h ago24:06

24:06

Drs Harrington, Rodriguez, and Ridker discuss the changing field of cardiac prevention, where imaging fits in, and the new concept of standard modifiable risk factor-less patients. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington Life's Essential 8: …

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How Evolved Models and Agentic Workflows Cut Your AI Costs Now 21:53

17h ago21:53

21:53

Are high AI usage costs crippling your budget? Many are overspending by defaulting to the newest, most expensive reasoning models for simple tasks. The problem: The temptation to use "the biggest brain" for every job, leading to ballooning token costs and slow performance. The solution: Discover the power of specialized, smaller models and asynchro…

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Oct 24 2025 This Week in Cardiology 30:24

3d ago30:24

30:24

The PREVENT score in hypertension, GLP-1 mechanism of action in cardiovascular disease, CAD type and statin benefit, and the problem with hospitalization endpoints in HF trials are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, v…

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Convert Your GPTs to Autonomous AI Agents NOW 25:35

8d ago25:35

25:35

Struggling with the limits of your custom GPT prompts? Lee and Rich discuss the essential shift from simple desktop prompts to full, autonomous, and scalable AI agents. You've hit the memory wall and document limits; it's time to untether your best workflows. Discover how graduating to an agentic platform with vector stores, persistent memory, and …

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Oct 17 2025 This Week in Cardiology 32:01

10d ago32:01

32:01

Another knock against the antiplatelet/anticoagulant combo, polypills in HF, the physical exam of the future, and the problem of underpowered trials that even Bayesian analyses cannot rescue are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or…

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The Ultimate AI Co-worker: How One Finance Team Found its AI Spark 31:50

15d ago31:50

31:50

A CFO shares how her finance team, initially hesitant about AI, found excitement and a path to business automation by participating in an AI-powered music video contest. The episode details how they went from creating a music video with tools like ChatGPT and Neural Frames to applying those same skills to their day-to-day financial tasks. They disc…

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Oct 10 2025 This Week in Cardiology 26:02

18d ago26:02

26:02

GLP-1 use in HFrEF, left atrial posterior wall isolation during AF ablation, peri-device leaks for LAAO, new findings in post-cardiac surgery AF, and imaging before AF ablation are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, v…

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Unlocking Longevity: Aging Reimagined 22:43

21d ago22:43

22:43

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Why AI Will Dismantle the SaaS Business Model 22:18

22d ago22:18

22:18

Software as a Service (SaaS) companies are overspending on 'SaaS fat'—bloated software with features nobody uses. The AI Guys reveal how the traditional per-seat licensing model is becoming outdated, inefficient, and expensive. They reveal how AI is set to disrupt the SaaS industry by automating tasks and providing a more efficient, cost-effective,…

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Oct 03 2025 This Week in Cardiology 26:50

24d ago26:50

26:50

Two great stories of translation science leading to beneficial drugs in terrible diseases of the heart and the Sisyphean task of predicting the need for pacing after TAVI are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: …

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How AI Is Disrupting Global Outsourcing 22:08

29d ago22:08

22:08

Offshoring was once a strategic move for cost savings and scalability, but the rules are changing. Join the AI Guys as they discuss how the rise of AI is making it possible for companies to bring jobs back onshore. They break down how AI agents are becoming the new offshore workforce, handling tasks like customer support and routine operations, hel…

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Sep 26 2025 This Week in Cardiology 22:50

1M ago22:50

22:50

A bold trial in valvular heart disease, a CV prevention trial whose message is humility, VTE dogma challenged, more news on oral GLP-1 agonists, and a few public service announcements are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to com…

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The Death of the Chatbot 20:11

1M ago20:11

20:11

Many businesses are still relying on traditional chatbot builders and live chat solutions that are tethered to a single channel and burdened by expensive seat licensing models. This episode explains why a platform-based approach is the future of business. Learn how to untether your AI agents, orchestrate them across multiple channels, and own your …

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Sep 19 2025 This Week in Cardiology 33:55

1M ago33:55

33:55

More trials at ESC, including PARACHUTE HF, DAPA ACT HF-TIMI 68, AMALFI, and a super-interesting modeling study of when to start oral anticoagulants in AF, are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.med…

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Nobel Laureate on Touch and the Joy of Scientific Discovery 23:44

1M ago23:44

23:44

The 2021 winner of the Nobel Prize in medicine, Ardem Patapoutian speaks of his love for science, why he wishes he had an MD, and the importance of getting out of the lab to inspire young people. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit: https://www.medscape.com/author/bob-harrington Nobe…

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AI Platforms vs. Workflow Engines: The Difference You Need to Know Now 18:35

1M ago18:35

18:35

Many businesses confuse a workflow engine with a comprehensive AI platform, leading to "spaghetti code" and unmanageable, brittle solutions. This episode clarifies the crucial difference, explaining why platforms are essential for centralized management, security, and control of your AI agents. Learn how to use a workflow engine as a component of a…

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Sep 12 2025 This Week in Cardiology 31:05

2M ago31:05

31:05

More from ESC including: Valvular HD guidelines, a new drug class for HTN, myosin inhibition in HCM, vericiguat, and digoxin are the topic discussed by John Mandrola, MD. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I New European Valvular Heart Disease …

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The Education Elephant: A Blueprint for AI in a Slow-to-Change Industry 39:50

2M ago39:50

39:50

Are you struggling to implement AI in a traditionally slow-to-change industry? Ed Buckley and Marlee Strawn, co-founders of Scholar Education, a platform using AI to transform learning, reveal their strategy for winning over skeptical teachers by co-designing a solution that reduces workload and personalizes student support. Learn how they're tackl…

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Sep 05 2025 This Week in Cardiology 38:01

2M ago38:01

38:01

The big beta-blocker story from ESC, dual pathway therapy with aspirin and OAC, stopping OAC after successful AF ablation, and DANCAVAS II trial are the topics John Mandrola, MD, discusses on this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/t…

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Don't Get Burned: How to Prevent Your Project from Failing Before It Starts 31:33

2M ago31:33

31:33

Is your company's AI project spiraling out of control? Many organizations get excited and push for rapid development, but without proper governance, a solid plan, and a focus on core problems, these projects can spread like a virus. They lead to chaotic development, wasted spending, and developer burnout. We discuss why a "build versus buy" mentali…

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Aug 29 2025 This Week in Cardiology 34:09

2M ago34:09

34:09

CAC 0 takes a gut punch, ICD therapies cannot be surrogates for benefit, and two important trials from ESC are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I CAC 0 LDL-C and CVD Risk With CA…

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Why Most AI Projects Fail Before They Start 33:38

2M ago33:38

33:38

Ever wonder why so many AI projects fail? In this episode, Rich and Lee expose the "missing middle" of AI—the intensive data science work that happens between collecting your data and getting real value from it. They share three foundational laws of AI that challenge common misconceptions. Learn why a large investment isn't the key to success and h…

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Aug 22 2025 This Week in Cardiology 26:05

2M ago26:05

26:05

John Mandrola discusses conduction system pacing vs standard pacing, withdrawing HF meds when AF is corrected and patient selection in LAAO. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Conduction System Pacing CSPACE trial https://doi.org/10.1016/j.ja…

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The Crucial Gap Between New AI Models and Your Business 28:12

2M ago28:12

28:12

Are new AI models like Grok 4 and ChatGPT-5 a game-changer for your business? This episode reveals that while the technology is advancing at a blistering pace, a significant cultural lag in human adoption is creating a disconnect. We break down why upgrading models isn't like upgrading software and how a "social media hangover" is hindering effecti…

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Aug 15 2025 This Week in Cardiology 23:29

3M ago23:29

23:29

Big new hypertension guidelines, ultraprocessed foods, coronary sinus reduction and evidence-based medicine, and more news on pulsed field ablation for atrial fibrillation are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit:…

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How to Overcome Your Team's Fear of Failure 42:29

3M ago42:29

42:29

Are your executives stressed about AI? Many companies face "analysis paralysis," fearing a high-stakes, overnight transformation. We're joined by Kurt Daniel, a 25-year software veteran and former Microsoft alum, who argues for a balanced approach. He shares how to create psychological safety for your team, encouraging them to experiment and even f…

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Aug 08 2025 This Week in Cardiology 31:57

3M ago31:57

31:57

Listener feedback on SURPASS CVOT, AF ablation and the limits of meta-analyses, a Watchman alert from FDA, and oral anticoagulation choices in elderly patients are discussed by John Mandola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape…

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Tools vs. Autonomous Agents - The Crucial Difference Explained 37:51

3M ago37:51

37:51

Are you struggling to scale your AI efforts beyond single-user tools? Many businesses confuse basic AI applications with robust, autonomous AI agents, leading to significant limitations. This episode dissects the critical differences between AI tools and agent platforms, revealing why security, scalability, and centralized management are vital for …

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Aug 01 2025 This Week in Cardiology 30:27

3M ago30:27

30:27

Exercise and CV outcomes, aldosterone modulation, AI for ECG reading, GLP-1 comparisons, end-of-life decisions, and another well-meaning policy that caused harm in veterans are discussed by John Mandrola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https:…

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Untangle Your AI: Workflow vs. AI Layer 25:37

3M ago25:37

25:37

Are you confusing AI with simple automation? Many businesses struggle to differentiate between AI layers and workflow automation, hindering their true AI potential. This episode dissects the "new stack," revealing how applications must be AI-ready, built with AI, and centered on a conversational user experience. Discover the critical middleware tha…

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July 25 2025 This Week in Cardiology 31:27

3M ago31:27

31:27

The VENTOUX study of endurance athletes, the 10,000 step myth was not busted, rate vs rhythm control for AF, and GLP1 drugs and observational studies are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.…

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No Going Back: The AI Revolution in Higher Education 32:29

3M ago32:29

32:29

Worried about AI in education? This episode features Jen Gillespie, an assistant professor redesigning her psychology courses at the University of South Florida to intentionally integrate AI. She shares her strategy for ethical AI use, focusing on transparent collaboration and proper citation. Discover how she guides students to use AI as a powerfu…

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Jul 18 2025 This Week in Cardiology 32:15

3M ago32:15

32:15

Finerenone, what not to consider when choosing treatment of AS, brain health after atrial fibrillation ablation, early rhythm control for AF, and Watchman reimbursement cuts are discussed by John Mandrola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https…