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Health shouldn’t feel this hard. I’ve lived it, studied it, and now I’m here to help make it make sense. A smarter, more human way to live well. Subscribe now, and start living well, for real. Instagram: @sarahannmacklin Newsletter: https://substack.com/@sarahannmacklin Website: sarahannmacklin.com #LiveWellBeWell
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Most of us are busier, more “optimized,” and more connected than ever - yet somehow feel less alive. Why? And what would it look like to reclaim a deeper, wilder sense of humanness in a world obsessed with control? This week, Oliver Burkeman, bestselling author of Four Thousand Weeks and Meditations for Mere Mortals, returns to explore the paradox …
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Watch the FULL podcast here: https://youtu.be/bj0-zUDFkxc Worried that your HRV looks “low” on your wearable? I ask what a low HRV actually means, why different devices produce different numbers, and when a change is worth paying attention to. This clip explores how to interpret heart rate variability without getting lost in the daily noise. We dis…
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Watch the FULL podcast here: https://youtu.be/Lw6iZbZBiw8 Thinking about TRT for low testosterone? This clip takes a closer look at who genuinely benefits from testosterone replacement therapy, what current evidence suggests about safety, and why fertility planning is crucial. I’m exploring with my guest how to distinguish primary from secondary hy…
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You’ve been told your phone is just a tool. But what if it’s quietly rewiring your motivation, eroding your focus, and crowding out the single chemical your brain craves most - connection? This week on Live Well Be Well, neuroscientist and author TJ Power joins me to explore the science of dopamine, focus, and digital balance. TJ, who developed the…
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Watch the FULL podcast here: https://youtu.be/C--vYFyHAEw What if your PMS symptoms aren’t just about hormones? In this episode, we dive into the cultural, biological, and emotional influences that shape your period experience - from why girls often grow up ashamed of their first cycle to how partners can play a powerful role in reducing PMS stress…
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Watch the FULL podcast here: https://youtu.be/XXwgXDeOYJI Not sure where to start with your health? The most effective first step, as I discuss here, is to identify the single habit acting as your biggest performance anchor and remove that brake before adding more tips and hacks. This clip explores the “brake vs accelerator” approach to health, why…
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This week’s guest, Mo Gawdat, former Google [X] Chief Business Officer and author of Solve for Happy, returns with a world-first: EMMA, an AI designed to help humans find and nurture true love. Why? Because loneliness is now epidemic, love has been commercialised, and so many of us feel burnt out by dating. EMMA aims to change the economics of love…
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Watch the FULL podcast here: https://youtu.be/AySFUeR1pw8 Are NAD+ drips or NMN supplements a smart way to support longevity? I connect what NAD+ actually is with what current human studies show and why dosage, delivery and safety still have big question marks. This clip takes a closer look at what NAD+ (nicotinamide adenine dinucleotide) does in c…
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Watch the FULL video here: https://youtu.be/hsaGZXiEbNs Most women don’t realize how much their hormones shape their metabolism and recovery or how wearables often get it wrong. In this clip, Dr. Stacy Sims breaks down what really happens to your insulin sensitivity and immune system throughout your cycle, why progesterone makes you temporarily mor…
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From growing up on food stamps to becoming one of the youngest full professors in the US, Dr. Andy Galpin’s story is nothing short of extraordinary. A world-leading human performance scientist, Andy shares the values of hard work and ambition instilled by his parents and how those principles carried him from adversity to academic success. But this …
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Inflammation isn’t always the enemy, it’s your body’s defense system. But when it gets out of control, it can silently drive arthritis, heart disease, gut issues, and even mental health struggles. In this episode, we break down what the Dietary Inflammatory Index (DII) actually shows, why plant protein and fiber lower inflammation, and how animal p…
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Are your supplements actually helping you, or just draining your wallet? In this episode, Dr. Stacy Sims breaks down the truth about three of the most popular supplements women buy: collagen, magnesium, and creatine.You’ll learn which type of collagen (if any) really supports joint health, why most collagen powders don’t count toward your daily pro…
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Most conversations about fertility focus on women. But here’s the truth: up to 50% of infertility cases are male, and men’s reproductive health is a powerful window into their overall wellbeing, longevity, and disease risk. This week’s guest, Professor Suks Minhas, world-leading consultant urologist and expert in male fertility, is here to change h…
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Can your menstrual cycle really change how you train, recover, and build strength - or is that just fitness hype? In this clip, we dive deep into the latest research on exercise and the menstrual cycle. While some studies suggest a small dip in performance during your period and more strength potential around ovulation, the evidence is mixed and of…
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How much protein do you actually need per day? In this clip, we break down the science of protein requirements by body weight and show what that looks like in real food examples. From Greek yogurt and nuts to tempeh and chicken, here’s a practical, evidence-based guide to daily protein intake. Rupy Aujla Listen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…
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You’ve been taught to think of your period as just that - a period. A monthly inconvenience to be managed with tampons and painkillers. But what if your menstrual cycle is actually a vital sign? A powerful, daily indicator of your brain, gut, and metabolic health that you’ve been taught to ignore? This week’s guest, Dr. Hazel Wallace - medical doct…
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Cordyceps mushrooms have been used for centuries, but what does modern science reveal about their effects on energy, oxygen uptake, and fertility? In this clip, we explore the evidence, separating tradition from data to uncover whether cordyceps can truly enhance vitality. Dr. Catalina Fernández Listen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠…
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Bleeding gums might be more than a dental issue. they could signal hidden risks for Alzheimer’s, heart disease, and even cancer. In this episode, we unpack how the oral microbiome drives inflammation, plaque buildup, and systemic disease. Could flossing actually add years to your life? Dr. Katie Lee Listen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠he…
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Protein is at the forefront of health and longevity research. But how much do you really need? And is it just about muscles, or does protein hold the key to aging well, preventing frailty, and protecting long-term health? This week’s guest, Dr. Rupy Aujla, NHS GP, nutritional medicine expert, and founder of Doctor’s Kitchen, takes us inside the sci…
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Learn about 12 powerful spices that help balance inflammation and support a strong immune system. In this conversation with Kanchan Koya, you’ll discover why chili lovers might live longer, and simple ways to add these spices to soups, teas, and everyday meals for better health. Dr. Kanchan Koya Listen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠…
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Is your mouthwash, toothpaste, or morning routine actually harming your oral health? In this conversation with Katie Lee, we explore the surprising truth about swishing water vs. mouthwash, the hidden risks of essential oils and oil pulling, and the heated debate on fluoride in toothpaste and tap water. Dr. Katie Lee Listen to the full episode⁠⁠ ⁠⁠…
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We’re not taught how to protect our brains. We’re not taught how food, sleep, and stress shape memory and mood. We’re not taught why dementia is rising or that prevention starts decades earlier. But we should be. This week’s Brain Health Masterclass brings together leading neurologists, scientists, and longevity experts to explore what really keeps…
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Is zone 2 training actually effective for women? In this conversation with Dr. Stacy Sims, she breaks down the science behind Zone 2 and explains why women may need to rethink how they train for fitness and longevity.Dr. Stacy Sims Listen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…
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Plastics aren’t just polluting the planet. They’re showing up in our bodies in ways we never imagined. From our brain to our bloodstream, even fertility treatments, microplastics are everywhere. This week’s guest, Dr. Robin Mesnage, toxicologist and researcher, reveals why microplastics and pesticides are far more pervasive than we realize, from ou…
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What if your immune system was shaping your personality without you even knowing? In this clip, immunologist Dan Nicolau reveals surprising science behind the mind-body connection, how curiosity and forgiveness affect health, and why infections like toxoplasmosis can radically change behavior. Dan Nicolau Listen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…
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Can medicinal mushrooms really support cancer treatment? Dr. Catalina Fernández explains how mushrooms may help strengthen the immune system, reshape the gut microbiome, and improve quality of life during conventional cancer care.Dr. Catalina Fernández Listen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Watch the full episode on YouTub…
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You might think depression looks like sadness, withdrawal, or losing all motivation. But what if it could also look like achievement, productivity, and relentless drive? This week’s guest, Dr. Judith Joseph, psychiatrist, researcher, and author of High Functioning Depression, reveals why so many high performers silently struggle with emptiness, anx…
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Doug Bopst opens up about the hidden costs of chasing perfection in fitness and life. From battling negative self-talk and saying yes to everything, to shifting his health priorities and repairing relationships, Doug shares lessons that go far beyond the gym. Doug Bopst Listen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠ Watch the full e…
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Artificial sweeteners promise a “sugar-free” solution, but what does the science actually show? In this conversation with Emeran Mayer, we explore their impact on the gut microbiome, metabolism, and long-term health, along with how sugar cravings are formed and whether soda myths hold up. Dr. Emeran Mayer Listen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠h…
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You think you know what’s stopping you from living a truly fulfilled, meaningful life. You blame lack of time, not enough money, or the constant pressure to do more. But what if the real barrier is how you define wealth and the way society has programmed you to chase success? This week’s guest, Robin Sharma, is a globally respected leadership exper…
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In this heartfelt episode of Five Questions to Nourish the Mind, Body & Soul, Katie Lee opens up about courage, personal growth, and the profound lessons learned through life’s biggest challenges. From a six-year journey to motherhood, to the smallest daily changes like honoring her body’s need for rest. Dr. Katie Lee Listen to the full episode⁠ ⁠⁠…
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Could shifting your eating window radically improve your sleep, energy, and mental clarity? In this clip, we explore the science and personal experience behind eating in a 4–6 hour window, finishing meals by early afternoon. Learn how meal timing affects sleep quality, why hunger before bed can be a good thing, and the fine line between discipline …
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You think you know what’s making you feel exhausted, anxious, or unwell.You blame stress, your hormones, or bad luck.But what if one of the biggest factors is in over half the food you eat and you’ve been told it’s “healthy”? This week’s guest, Milli Hill, is an award-winning journalist, speaker, and author whose latest work reveals the hidden role…
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In this 5 Questions episode, we invite Simon Sinek to speak straight from the heart. From overcoming self-doubt to redefining his relationship with sugar, and learning how listening changed everything, each answer offers unexpected wisdom. Listen to the full episode⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here…
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Struggling with gut health but not sure where to begin? Dr. Emily Leeming shares a practical guide with five easy, evidence-backed changes you can implement right now to support your microbiome, digestion, and even mental clarity. Learn how fiber, fermented foods, polyphenols, dietary diversity, and a simple breathing technique can transform your g…
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You think you know what resilience looks like. You picture someone gritting their teeth, pushing through, holding on tight. Someone who climbs mountains without oxygen, survives avalanches, makes it to magazine covers. This week’s guest, Cory Richards, did all of that. He isn’t just a world-renowned climber and National Geographic photographer, he’…
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What if everything you thought about healing was incomplete? In this 5 Questions episode, Dr. Emilia Vuorisalmi shares the lesser-heard truth behind wellness trends, love addiction, emotional burnout, and the power of simply learning how to breathe again. We explore why self-worth, presence, and storytelling may be the most vital tools for health.D…
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In this thought-provoking conversation, we explore the deep connection between meaning, wisdom, and growth. From the misunderstanding of meaning in modern culture to the importance of shared wisdom, we dive into how self-deception and trauma shape our lives. Is wisdom something we can cultivate alone? John Vervaeke Listen to the full episode⁠ ⁠⁠⁠⁠⁠…
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Your neurons can become younger. Your gut can reshape itself in five days. Your immune system can learn to fight cancer. This isn't theory. It's mycology. And it's about to change how you think about what your body can do. This week on Live Well Be Well, I sit down with Dr. Catalina Fernández de Ana Portela, a pioneering mycologist and oncologist w…
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How does emotional health influence your physical well-being? In this video, Kate Tolo shares her personal journey of how addressing emotional barriers helped transform her diet and overall health. Can emotional healing unlock lasting physical health? Watch to discover how emotional health is the key to unlocking a better, healthier you. Kate Tolo …
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What does it cost to follow your own map?Dr. Emeran Mayer, pioneer of the mind-gut connection, shares the unexpected choices that defined his life from resisting conformity to overcoming early fears. In this short, reflective episode, he explains why one small change rewired his path and what he still struggles to make peace with. Dr. Emeran Mayer …
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Trigger Warning: This episode includes discussion of trauma, suicide, abuse, and emotional processing in the context of psychedelic therapy. Please take care while listening. Viewer discretion is advised. You've been told psychedelics are poison. That healing trauma requires years of talk therapy. What if three sessions could change everything? Thi…
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Sprouts are one of the most nutrient-dense, accessible foods on the planet. In this clip, Doug Evans explains how these tiny plants boost protein, reduce anti-nutrients, and grow without soil or sunlight, making them a simple, powerful upgrade to any diet. Listen to the full episode ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Watch the full episode on YouTube⁠ ⁠⁠⁠…
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What happens when you achieve everything you set out to, and still feel empty? In this conversation with Simon Sinek, he shares the painful turning point that led to Start With Why, how ADHD became his greatest asset, and why so many exceptional leaders carry hidden struggles. The answers aren't in performance, they’re in self-awareness, vulnerabil…
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You've been told your hormones make you irrational.That menopause means cognitive decline, your emotions are just chemistry gone wrong, and your brain is simply too complicated to understand.Science says otherwise. This week's guest, Dr. Sarah McKay, is a neuroscientist, author, and brain health expert who's spent her career dismantling the myths w…
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Does understanding your menstrual cycle unlock better health, fertility, and performance? In this conversation with Dr. Stacy Sims, she breaks down the four phases of your cycle, reveals why anovulatory cycles are becoming more common, and explains how stress, diet, and lifestyle directly impact your hormones. From tracking your bleed patterns to u…
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What if the drug that could save your life… already exists? In this powerful story from David Fajgenbaum, you'll hear how a man on the brink of death discovered an existing drug, never approved for his illness, that brought him back. But the real shock? No one profits from it, so no one’s looking. Learn the hidden world of drug repurposing, AI-driv…
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Your gut isn't just about what you eat. It’s about how you live, love, feel, and breathe. In this episode of Live Well Be Well, I sit down with Emily Leeming, PhD, gut-brain researcher at King's College London and registered nutritionist whose work bridges the gap between cutting-edge microbiome science and practical wellness, to uncover the hidden…
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What if failure isn’t the problem, but the solution? In this video, we unpack the neuroscience of fear, failure, and self-compassion. We explore how small changes like a single cup of greens or taking the first uncomfortable step can rewire the brain. This isn’t about hacks. It’s about mindset, values, and learning to see failure as information, no…
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