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Genomics Revolution

Brad Goodner

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Podcast associated with Hiram College Genetics course. Focus is on the history of genomics and how a genomic view of life has impacted basic science as well as applied fields such as medicine and agriculture.
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Join Dr. DNA Dan as he dives deep into the world of genetics, genomics, DNA, and the future of precision genomic medicine. Dan discusses topics ranging from health and ancestry genetic testing, forensic genetics, genetics, and mental health, common myths about genetics, and more. DNA Dan, SCU Professor of Genomics, Dan Handley, M.S., Ph.D., shares his knowledge from his over 30 years of experience in the world of advanced genomics research and biotechnology. For more information about Southe ...
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Welcome to For Whom the Cell Tolls! This cast explores the fascinating stories of Biology that I've encountered in my journey as a Biology Professor and lymphoma scientist at Minnesota State University and my previous experience at Mayo Clinic. Major themes to be explored include cancer, tumorigenesis, new therapy mechanisms, immunology, life/death, disease ecology, microbiology, and evolution, among others. I try to integrate philosophy, culture, and the arts alongside emerging Biology find ...
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The New England Biolabs podcast series, Lessons from Lab and Life, is dedicated to sharing helpful life lessons from successful scientists. From an overview of cutting edge research to finding sources of inspiration, our podcast is for science enthusiasts that like to ponder "what it all means". Listen as leading researchers draw lessons from where scientific concepts (and misconceptions) have come from, where they are now, and where they are headed in the not-too-distant future. If you've g ...
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When Science Finds a Way is the science podcast that tells the human story. Join botanist-turned-Hollywood actor Alisha Wainwright as she meets the scientists and communities turning bold ideas into real world impact. This season, you'll hear about how new medical imaging tools are helping us see our bodies in ways we never could before, meet the team using climate data to predict and prevent disease outbreaks, and learn about how engaging with the arts can help improve our mental health. - ...
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Secrets From the Crime Lab

practicalforensics.science

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A podcast for practitioners, professionals, and enthusiasts of forensic science, applied science, and science related topics: exploring the truth of true crime. Learn about the real forensic science behind the cases, how it actually works behind the closed doors of the crime lab, and what happens when it fails or is misunderstood. Hosted by a scientist with over twenty years of laboratory experience, this podcast discusses the challenges and nuances of the forensic fields from her own experi ...
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A good mentor can be the difference between success and failure. But what to do if you don't have help on hand? Mentors At Your Benchside provides curated help and advice from experienced researchers on various topics, from lab skills and techniques to career progression. Each short episode is bursting with easy-to-access help and advice that can improve your results and help you get the most out of your time in the lab. https://bitesizebio.com/mentors-at-your-benchside
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Outsmart Your Genes – A Podcast by Sequencing.com Your DNA doesn’t define you—your choices do. Outsmart Your Genes is the podcast that empowers you with genetic insights to take control of your health. Brought to you by Sequencing.com, we explore how whole genome sequencing, AI-driven analysis, and precision medicine are revolutionizing healthcare. Every episode features leading experts, patient advocates, and real-life stories of individuals using their genetic data to prevent disease, opti ...
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The Covid-19 pandemic laid bare a truth we can't ignore: vaccine equity, the principle that everyone should have fair and timely access to life-saving vaccines, is still out of reach for many. This is especially true across Africa, where local manufacturing supplied less than 1% of the vaccines used. But change is happening. Alisha sits down with D…
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Food production drives nearly a third of global greenhouse gas emissions. So how do we help people choose meals that are good for their health, and the planet? Alisha sits down with Professor Pete Scarborough, who's co-leading research to help decision-makers and the public make better informed choices. We also meet Jo, who's testing a digital tool…
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A significant gap remains in effective mental health interventions for young people. Addressing this gap is crucial, and approaches like problem-solving therapy could offer a practical, accessible solution within educational settings. Alisha and Professor Vikram Patel discuss a school-based trial in India that's exploring a new way forward: POD (Pr…
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Vaccine breakthroughs dominated the news during the Covid-19 pandemic. But they weren't the only scientific innovations changing how we understood the virus. Across Europe, a team of pathologists, technologists and imaging researchers saw a gap: we needed better technology to see what was really happening inside the lungs of individuals who died af…
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Hear from Valadimir Potapov, a Bioinformaticist here at NEB and an important part of the team that builds online tools to aid both NEB scientists and our customers in calculations and experimental design. Valdimir joins us to talk through the open access Ligase Fidelity Tools which are used to aid in the design of DNA Assembly via the Golden Gate m…
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By the time we realise an outbreak is underway, the disease is already spreading, and the window to act is closing fast. But what if we could get ahead of it? Over the past decade, scientists and technologists have been developing powerful modelling tools that combine health and climate data to forecast where and when outbreaks might occur. Alisha …
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Navigating healthcare can be particularly challenging for autistic people. Reasons for this are complex, but for women and people assigned female at birth, the problem is compounded by a lack of representation in autism research, leaving healthcare services ill-equipped to meet their specific needs. Alisha speaks with Dr Aimee Grant about a groundb…
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We know that singing, painting and other creative outlets can boost our mental health. But how do we harness the therapeutic power of the arts? Alisha speaks with UK researcher Professor Daisy Fancourt, whose work is helping to establish the arts as a key ingredient in conversations about mental wellbeing, alongside diet and exercise. She also meet…
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When Science Finds a Way is back! Join botanist-turned-Hollywood actor Alisha Wainright as she meets the scientists and communities turning bold ideas into real world impact. This season, you'll hear about how new medical imaging tools are helping us see our bodies in ways we never could before, meet the team using climate data to predict and preve…
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Welcome to our most CONTROVERSIAL episode yet! We address “Turbo cancer” (idk what’s specifically meant by this still but I outline the likely/historical geneses behind these cases), inflammation issues, central dogma basics, mRNA vaccine tech, the rise of the microbiome and its importance for health, and the likely (yet boring) underlying sources …
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Dr. Carolyn Bertozzi's impact in the field of glycosylation has been profound, enabling on our current understanding of disease and inflammation presentation and potential vehicles for treatment. Dr. Bertozzi was awarded the Nobel Prize in 2024 for the development of biorthogonal chemistry, and she explains how this understanding can impact disease…
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Hearing voices is a challenging symptom of psychosis that treatments have often failed to address effectively - until now. Introducing AVATAR therapy, a remarkable approach using digital technology to help patients engage with distressing voices and regain control. Alisha meets Dr Vaughan Bell to explore the therapy's potential, talk about findings…
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Dr. Ben Lynch, pioneer in epigenetics and Nutrigenomics and author of Dirty Genes, discusses the profound impact of understanding our genetic blueprint and how personalized strategies can optimize health. He introduces his tool, StrateGene, a comprehensive genetic analysis that enables individuals and practitioners to develop precise health plans b…
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Genomics has revolutionised cancer research, offering new hope for cancer diagnosis and treatment. But there are challenges ahead. Alisha is joined by Dr Peter Campbell and researchers Dr Solomon Rotimi and Sara Gómez Trillos to discuss the breakthroughs and the issue of ensuring fair access to advancements for patients worldwide. When Science Find…
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Despite efforts to eliminate cholera by 2030, it remains a formidable global threat. Could technology hold the key to combating this deadly disease? Alisha sits down with Professor Iruka Okeke to talk about the factors driving cholera's spread and the innovative mapping techniques being used in Kenya to identify hotspots. When Science Finds a Way i…
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Over the years, the reluctance to include pregnant participants in vaccine trials has been increasingly challenged. That's because their inclusion can make vital medications available during pregnancy and provide data that could improve survival rates for both parent and baby. Alisha is joined by Dr Flor M Munoz, a global expert in maternal immunis…
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As rising temperatures challenge vulnerable regions, could 'cool roofs' be the affordable, sustainable solution? Alisha joins Dr. Aditi Bunker to talk about the remarkable health benefits uncovered in Burkina Faso's trial, hearing firsthand accounts of how this simple intervention significantly reduces indoor temperatures, lowers heart rates, and i…
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Exercise is more than just fitness – it can be a powerful tool for mental health. But what actually occurs in the brain during a workout, and how can it help in treating mental health issues? Alisha meets Dr Jonathan Roiser and his team of researchers to uncover insights from a groundbreaking pilot study exploring brain activity during exercise, in…
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In this episode, we explore Nicole Castellano's remarkable journey from her diverse career as a pilot, world-class skater, and entrepreneur to confronting a mysterious illness that began a 12-year diagnostic odyssey. We discuss the challenges inherent in diagnosing rare conditions like porphyria, the transformative role of genetic testing, and the …
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Wildfires are intensifying globally, posing threats to health and Indigenous communities. Join Alisha and Dr Nicole Redvers as they explore cultural burning, a traditional Indigenous technique offering a potential solution to modern wildfire challenges and hear from those bridging traditional practice and science. A fascinating conversation on the …
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Diseases like dengue, yellow fever and Zika claim over 700,000 lives a year. But a breakthrough from the most unlikely of places could be about to change all that. Travel to Colombia to see how Professor Scott O'Neill, founder of the World Mosquito Program, is using mosquitoes infected with a naturally occurring bacterium as part of a game changing…
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#115 — Hepatocytes are liver cells that are essential for its function. They are also essential for certain branches of drug testing and diagnostics. However, they have irregular shapes, multiple nuclei, and can clump, which makes them difficult to process and count accurately. In this episode, we explain how to prepare the best hepatocyte samples …
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More incredible stories of how scientists and communities are leading the charge against urgent health challenges. Join botanist-turned-Hollywood actor Alisha Wainwright as she explores groundbreaking research and pioneering innovations transforming the science of health. From traditional wildfire management approaches — rooted in Indigenous practi…
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In this episode of Outsmart Your Genes, Dr. Jeremy Koenig sits down with Dr. Jason Siefferman, a triple board-certified physician specializing in physical medicine, rehabilitation, interventional pain medicine, and headache medicine. As the founder and medical director of Manhattan Pain Medicine, Dr. Siefferman shares his expertise in diagnosing an…
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#114 — High-quality nuclei extraction is pivotal for many genetic and epigenetic studies, including single cell RNA-seq to describe transcriptomic profiles and gene expression dynamics and ATAC-seq to determine chromatin accessibility. But nuclei samples are extremely delicate and can be challenging to prepare and count. In this episode, we provide…
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In this episode, we welcome Denise Morrow, a trailblazer in patient advocacy whose personal diagnostic odyssey led to groundbreaking health discoveries. After decades of searching for answers, whole genome sequencing enabled her to identify a primary CoQ10 deficiency, dramatically improving her health and inspiring her to launch Genetics for Health…
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In this episode, Dr. Jeremy Koenig sits down with Dr. Brandon Colby, a pioneer in predictive medicine and CEO of Sequencing, to explore how whole genome sequencing is transforming healthcare. Dr. Colby shares his personal journey of living with a rare genetic disease, which fueled his mission to revolutionize disease prevention. They discuss the sh…
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In this episode of 'Secrets from the Crime Lab,' host Angela Swarts returns after a brief hiatus to delve into an enlightening conversation with William Losefsky of Investigative Concepts. With a background in law enforcement and extensive experience in private investigation, Losefsky shares his expertise in forensic death investigation, drug diver…
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The three Passion in Science Award winners in the Category of Arts and Creativity joined us in the studio to talk about their art and what initiated its creation. Sam Siljee shares his soundscapes, Sally Kong describes her weaving patterns, and Michael Weiner his details his uniquely scientific large-scale portraits.…
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This episode of 'Dr. DNA Dan' hosted by Professor Dan Handley from Southern California University of Health Sciences delves into genetics, specifically focusing on short tandem repeats (STRs). The podcast explains the significance of STRs in forensic DNA testing and paternity tests by measuring the number of repeated sequences in different individu…
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Welcome to a special episode where I'm joined by 11 of my Minnesota State students as we close out our Cancer Biology lecture! We weave through discussions surrounding generational causes of cancer, potential next-generation hallmarks, treatment & financial ethics, and what the future hold for this disease as a whole. All said, this one is super fu…
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In this episode, Dr. Dan Handley takes us into the fascinating world of proteins—those powerhouse molecules that do the heavy lifting in our bodies. While the human genome contains about 20,000 protein-coding genes, these genes produce over 100,000 different proteins, thanks to nature's incredible complexities. Dr. Handley breaks down the science b…
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#113 — Learning how to respond to criticism is an unavoidable aspect of grant applications. Follow all instructions from funding agencies to avoid immediate rejection. This episode of Mentors At Your Benchside gives you some simple strategies to ensure you respond to criticism in a constructive and proportionate way. For example, identifying review…
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The basic answer is no. When faced with R-CHOP resistance, DLBCL patients now have the option to utilize genetically modified Chimeric Antigen Receptor T-cells (CAR-T) designed to hunt tumors. This episode investigates the recent controversy into if these super-cells can transition into a villainous tumor themselves. We cover a paper by Garcia et. …
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#112 — Isoelectric focusing (IEF) is a powerful technique distinct from the more familiar SDS-PAGE, [1,2] tailored for separating proteins or peptides based on their isoelectric points (pI). [3] This method capitalizes on the migration of charged molecules through a stable pH gradient until they reach a zone where their net charge is zero, halting …
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#111 — In this episode, we dive deep into the fascinating world of microbes and their revolutionary applications in biotechnology. From environmental solutions to breakthroughs in health and medicine, microbes hold the key to some of the most advanced scientific developments. Discover how these microscopic organisms are transforming industries and …
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#110 — Comparing two sets of data is a fundamental process in statistical analysis, crucial for drawing meaningful conclusions across various fields. Whether it's for determining the success of an intervention, understanding market trends, or validating scientific research, the need for comparison arises. This episode delves into the essence of dat…
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#109 — How do you build a scientific network that gives you the best chance of getting your research funded? How can you identify who to include in your network, and how should you contact them? This episode explains how to build a scientific network that works for you. We discuss the answers to these questions and provide some examples of collabor…
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#108 — What should you use to fix your cells? Alcohols or aldehydes? Gluteraldehyde or formaldehyde? And how long will your cells stay fixed? This episode explains the four main fixatives for histology and cytometry and when to use them. It also provides some practical tips to ensure your fixation works and explains the benefits of combining fixati…
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#107 — Need to give your microscope a quick clean to get rid of some grime but unsure what cleaning agent to use? Have you had a nasty sample on there recently and need to disinfect it for the next user? This episode gives you a quick guide to disinfecting your microscopes, including what solvents are safe to use and the parts you should tackle fir…
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