The Clinical Problem Solvers is a multi-modal venture that works to disseminate and democratize the stories and science of diagnostic reasoning Twitter: @CPSolvers Website: clinicalproblemsolving.com
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Clinical Problem Solvers Podcasts
Reinvent Healthcare provides support, insight, and cutting edge information for health and wellness practitioners passionately committed to transforming our broken, disease-focused, healthcare system. Dr. Ritamarie Loscalzo, the founder of the Institute of Nutritional Endocrinology, shares more than 30 years of clinical experience using science-based, nutritional and natural approaches for successfully correcting the imbalances that lead to chronic disease. Her vast knowledge, infectious ene ...
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Episode 437 – RLR – An Abnormal Normal Gap Acidosis
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36:08https://clinicalproblemsolving.com/wp-content/uploads/2026/01/RLR-FINAL.mp3 Episode description RLR discuss a case of a normal gap acidosisBy rabihgeha
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This Scan Predicts Heart Attacks Before Symptoms Start (Even with Normal Labs)
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47:11What if you could detect heart disease before symptoms appear, before the first stroke, before the fatal heart attack, before the diagnosis? In this episode of ReInvent Healthcare, Dr. Ritamarie sits down with Joseph Ence, founder of Vasolabs, to explore a powerful and underused cardiovascular screening tool. Most people think normal labs mean a he…
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Episode 436: The Clinical Unknown Series – New Year, New Episode!
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58:59https://clinicalproblemsolving.com/wp-content/uploads/2026/01/CUS-1-2026.wav Ring in the New Year with a fresh episode! Join Debora, Mark, and Noah in the latest Clinical Unknown Series as they unravel a puzzling case together. Let’s start the year learning! To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here …
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Why Normal Labs Miss Early Metabolic Damage and What to Test Instead
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16:58What if your client’s “normal” labs are hiding mitochondrial breakdown, immune dysfunction, and early insulin resistance? In this episode, Dr. Ritamarie exposes why the standard lab panels so many practitioners rely on are failing and walks you through the functional markers that actually reveal root-cause imbalances. You’ll learn how to detect ear…
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How Bioenergetics Impacts Hormones: Energy Tools for Burnout, Mood & Fertility
43:56
43:56
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43:56What if your clients’ chronic fatigue, mood swings, or fertility struggles weren’t just biochemical but bioenergetic? In this episode of ReInvent Healthcare, we dive into a groundbreaking view of hormone balance that goes beyond nutrition and labs. Dr Ritamarie and Dr. Larisa Sharipova share how frequencies, emotions, and subtle energy patterns inf…
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What Teens Really Need for Health: Four Brothers Reveal the Truth About Anxiety, Sleep, and Energy
42:27
42:27
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42:27What if the leaders of the next health revolution aren’t doctors or scientists but four teenagers? In this uplifting and powerful episode of ReInvent Healthcare, Dr. Ritamarie sits down with the Ansari brothers, Abdullah (18), Zain (14), Emaad (12), and Qasim (10), known as The Holistic Kids. These young wellness advocates are authors, podcasters, …
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Episode 435: Neurology VMR – Weakness and numbness
1:02:37
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1:02:37https://clinicalproblemsolving.com/wp-content/uploads/2025/12/neuro_vmr_ep.dec25.mp3 Episode description: We continue our campaign to #EndNeurophobia, with the help of Dr. Aaron Berkowitz. This time, Sarah presents a case to Sebastian and Vijay. Sarah Blaine (@sarahkblaine) Sarah Blaine is an MD/MSc student at Emory University School of Medicine ap…
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Episode 434: Schema Episode – Eosinophilia
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57:01https://clinicalproblemsolving.com/wp-content/uploads/2025/12/Schema_12_10_15.mp3 Noah presents a fascinating case involving eosinophilia. Tune in as Maddy, Mark, and Youssef work through the diagnostic puzzle. To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here RLRCPSOLVERS…
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Beyond Oncology: Functional Strategies to Support Cancer Patients and Survivors
57:16
57:16
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57:16What if the biggest gap in cancer care isn’t the treatment but what happens before and after? In this episode of ReInvent Healthcare, Dr. Ritamarie Loscalzo is joined by Dr. Nalini Chilkov, founder of the American Institute of Integrative Oncology Research and Education (aiioRE.com), to explore how functional practitioners can fill the urgent void …
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The Genetic Code Behind Insulin Resistance, Fatigue, and Weight Gain
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27:34Struggling to understand why someone’s metabolic health isn’t improving despite clean labs and healthy habits? The missing piece might be written in their DNA. In this episode of ReInvent Healthcare, we uncover how key genetic variants (SNPs) can help you identify hidden metabolic risks and choose the right lab tests to confirm them. Discover how t…
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https://clinicalproblemsolving.com/wp-content/uploads/2025/12/Case-158-1.mp3 Episodic description RLR discussed a case of a red leg Student discount https://www.rlrcpsolvers.com/student-discounts/ IMG discount Use coupon code RLRIMG at check out https://rlrcpsolvers.com/annual-planBy rabihgeha
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Episode 432 – Spaced Learning Series – subacute inflammation
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38:07https://clinicalproblemsolving.com/wp-content/uploads/2025/12/MORAD-SLS-2.mp3 Download CPSolvers App here RLR CPSolvers In this new SLS episode, Maryana presents a case to Austin, Oumaima, and David as they navigate the waves of subacute inflammation and abdominal pain.By maryanahsmendonca
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Fasting for True Healing: What Most Practitioners Are Missing
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1:31:35What if the key to unlocking deep cellular repair, reversing disease, and reclaiming your energy was... not eating? In this episode, Dr. Ritamarie sits down with world-renowned water fasting expert Loren Lockman to explore how fasting goes beyond trendy biohacks, tapping into our body’s built-in healing intelligence. From detox-resistant weight gai…
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Episode 431: The Clinical Unknown Series with Anmolpreet Kaur
1:00:54
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1:00:54https://clinicalproblemsolving.com/wp-content/uploads/2025/11/CUS-Nov-20-post.wav In this exciting podcast episode, Anmol teams up with Mark for a compelling case discussion that you won’t want to miss! To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here RLRCPSOLVERS…
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Empower Your Clients to Rebel: Questioning Doctors, Rethinking Labs, and Taking Back Control
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11:16
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11:16What if the path to healing begins with rebellion? In this episode of ReInvent Healthcare, Dr. Ritamarie Loscalzo takes you deep into the radical idea that transformation doesn’t begin with protocols but with questions. Too many people accept dismissive diagnoses, symptom-suppressing prescriptions, and “normal” lab results that overlook early signs…
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Episode 430: WDx #39: Clinical Unknown with Drs. Kuchal Agadi and Ann Marie Kumfer
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59:15In this episode of WDx, Cheryl, Kaylin, and Sharmin are joined by Kuchal and Ann Marie, two wonderful members of the CPSolvers Academy. Kuchal presents a case of a young man with fevers to Ann Marie and Sharmin. https://clinicalproblemsolving.com/wp-content/uploads/2025/11/WDx-11.13.25-final.mp3 Download CPSolvers App here RLRCPSOLVERS…
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Uncovering the Hidden Causes of Long COVID and Chronic Fatigue: What Most Protocols Miss
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50:39Most people think of long COVID as something new, but for many, it’s simply a different name for an old, complex pattern: chronic fatigue. In this episode of ReInvent Healthcare, Dr. Ritamarie sits down with Dr. Evan Hirsch (The EnergyMD) to discuss the clinical connections between long COVID, chronic fatigue syndrome (ME/CFS), and the deeper bioch…
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https://clinicalproblemsolving.com/wp-content/uploads/2025/11/RLR-154-RTP-FINAL.mp3 Check out WAY more RLR content @ rlrcpsolvers.com where you can also find discounts for students and IMGBy rabihgeha
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Neuropathy’s Hidden Causes: What Labs and Protocols Often Miss
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16:16Most people think neuropathy shows up after a diabetes diagnosis. But in reality, tingling, numbness, or burning in the hands or feet often shows up years earlier. In this episode of ReInvent Healthcare, I explore the deeper drivers of neuropathy, beyond what conventional medicine typically considers, and share how to identify and address them befo…
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Episode 428: Neurology VMR – Diplopia and fever
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59:12https://clinicalproblemsolving.com/wp-content/uploads/2025/11/Neuro-Podcast-NeuroBehcet.mp3 Episode description: We continue our campaign to #EndNeurophobia, with the help of Dr. Aaron Berkowitz. This time, Dr. Yousuf Patel presents a case of diplopia and fever to Vale and Sebastian. Yousuf Patel Dr. Yousuf Patel is currently a resident in neurolog…
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Episode 427: Schema Episode – Schistocytes
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53:33https://clinicalproblemsolving.com/wp-content/uploads/2025/10/Schistocytes_Final.mp3 Youssef presents a fascinating case involving schistocytes. Tune in as Mark, Maddy, and Noah work through the diagnostic puzzle. Schistocytes Schema To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here RLRCPSOLVERS…
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Peptides for Autoimmune Healing: When and How to Use Them
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26:25Peptides are everywhere right now, in social media, practitioner circles, and supplement protocols. But are they really the solution for autoimmune and gut healing… or just another overhyped tool? In this episode of ReInvent Healthcare, Dr. Ritamarie Loscalzo is joined by functional health experts Steph Jackson and Jennifer Whitmire to explore how …
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Episode 426: Antiracism in Medicine – Episode 29 – Clinician Burnout, Racial Health Inequities & Reincorporating Rest into the Profession
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1:02:56https://clinicalproblemsolving.com/wp-content/uploads/2025/10/EPISODE-29-Clinician-Burnout-FINAL.mp3 CPSolvers: Antiracism in Medicine Series Episode 29 – Clinician Burnout, Racial Health Inequities, and Reincorporating Rest into the Profession Show Notes by Asya Pitre October 29, 2025 Summary: In this episode, hosts Ashley Cooper and Sud Krishnamu…
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How Insulin Resistance Damages Kidneys, And What Labs Catch It Early
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18:02What if your patient’s blood sugar looks “okay,” but their kidneys are already under attack? In this episode of ReInvent Healthcare, Dr. Ritamarie uncovers the common progression of kidney damage fueled by insulin resistance and elevated glucose. Most practitioners miss the early clues. And most patients never feel symptoms… until it’s too late. Di…
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Episode 425: Schema Episode – Ground Glass Opacities
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50:08https://clinicalproblemsolving.com/wp-content/uploads/2025/10/Schema-Episode-_Final.mp3 Maddy presents a fascinating case of dyspnea with diffuse ground-glass opacities. Tune in as Mark, Youssef, and Noah work through the diagnostic puzzle. GGOs Schema Bird + Lung Ddx References: NEJM CPC: Hypoxemia at the Bedside — https://www.nejm.org/doi/full/10…
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From Fat to Fibrosis: The Silent Liver Shift Most Practitioners Miss
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25:21One in three adults now has fatty liver disease, and most don’t even know it. It’s become the most common form of liver dysfunction worldwide—even outpacing alcohol-related liver damage. And the real danger? It often progresses in silence, from fat to inflammation to fibrosis, with no symptoms until it's too late. In this episode of ReInvent Health…
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Episode 424 – The Clinical Unknown Series with Debora, Mark, Noah and Rabih
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49:04https://clinicalproblemsolving.com/wp-content/uploads/2025/10/CUS-Rabih-Oct-2025-post.wav In this new episode, Rabih shares an important case with Debora, Mark, and Noah. We invite you to listen and join in on their journey as they work together to discover the final diagnosis. To join us live on Virtual Morning Report (VMR) or to present a case to…
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Nutrition for Inflammation and Autoimmunity: What Most Protocols Miss
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39:34
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39:34Inflammation is the biological fire underlying most chronic disease. In this episode, Dr. Ritamarie Loscalzo returns with NEPT graduates Steph Jackson and Jennifer Whitmire to uncover how food fuels or fights inflammation. From autoimmune flares and brain fog to hidden cardiovascular risks, the trio explores how everyday foods, even so-called “heal…
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Episode 423 – RLR – Neutrophilia s/p CABG
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57:02https://clinicalproblemsolving.com/wp-content/uploads/2025/10/RLR-PODCAST.mp3 Episode description RR discuss a case of AKI Student discount https://www.rlrcpsolvers.com/student-discounts/ IMG discount Use coupon code RLRIMG at check out https://rlrcpsolvers.com/annual-planBy rabihgeha
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Episode 422: WDx #38: Clinical Unknown with UCLA Cardiology fellows
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1:03:42Kaylin and Sharmin were joined by UCLA Cardiology fellows, Drs. Rachel Ohman and Angela Duvalyan, to discuss a case of a 49 year old woman with acute chest pain. Angela Duvalyan, MD is a second year Cardiology Fellow at University of California, Los Angeles (UCLA). Her clinical interests include interventional cardiology, medical education, and cli…
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From Freaked Out to Fired Up: Helping Clients Step into Healing with Confidence
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52:34What if the biggest block to your client’s healing isn’t the protocol but their fear of change? In this episode of ReInvent Healthcare, Dr. Ritamarie sits down with mindset and motivation expert Toni St. Clair to uncover what really stops clients from moving forward, and how you can become the kind of practitioner who inspires lasting transformatio…
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Beyond Health Coaching: What It Really Takes to Help Complex Clients
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41:07What if your patient’s “normal labs” were hiding a serious disease? What if protocols were making them worse, and you didn’t know? In this episode, Dr. Ritamarie Loscalzo sits down with functional nutrition experts and NEPT grads Steph Jackson and Jennifer Whitmire to challenge the shallow training and one-size-fits-all approaches flooding the heal…
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Episode 421: Baby on Board – and a surprise guest! Listen to Greg and Bobby discuss how to manage the guest tagging along for the ride!!
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56:37
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56:37Case Presenter: Anna Jarvis, MD Anna Jarvis is a current 3rd year OB/GYN resident at Johns Hopkins. She is originally from California, where she completed her MD at University of California, Irvine. She is currently applying to Maternal Fetal Medicine Fellowship this cycle! Case Discussant MFM Fellow – at University of Pennsylvania Greg is a curren…
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Liver-Pancreas Crosstalk: The Silent Breakdown Driving Insulin Resistance
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12:06What if the first signs of insulin resistance have nothing to do with glucose? In this episode of ReInvent Healthcare, Dr. Ritamarie uncovers the hidden metabolic dialogue between the liver and pancreas. It’s a connection that begins to break down long before glucose or A1C raise red flags. Beneath the surface of “normal labs” lies a growing storm:…
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Episode 420: Antiracism in Medicine – Episode 28 – SGIM 2025: Immigrant and Refugee Health
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43:00https://clinicalproblemsolving.com/wp-content/uploads/2025/09/Episode-28-CPSolvers-Antiracism-in-Medicine-Series-FINAL-AUDIO.mp3 CPSolvers: Anti-Racism in Medicine Series Episode 25 – Immigrant and Refugee Health: Live from SGIM 2025: Best of Antiracism Research at the Society of General Internal Medicine’s Annual Meeting Show Notes by Alec J. Cala…
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Episode 419: Neurology VMR – Headache and diplopia
52:31
52:31
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52:31https://clinicalproblemsolving.com/wp-content/uploads/2025/09/Timeline-1.mp3 We continue our campaign to #EndNeurophobia, with the help of Dr. Aaron Berkowitz. This time, Jeffrey presents a case of headache and diplopia to Vale and Sebastian. Neurology DDx Schema Jeffrey Shen Jeffrey is an academic rheumatologist whose early love for guessing TV pl…
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https://clinicalproblemsolving.com/wp-content/uploads/2025/09/IDLove-Episode-Colitis-1.mp3 Schema PDF To join us live on Virtual Morning Report (VMR) or to present a case to us, sign up here. Download CPSolvers App here RLRCPSOLVERSBy saklawi1
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The Hidden Hormone Imbalance Before Menopause Hits
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55:03Hot flashes, mood swings, and brain fog. Too often, these symptoms are brushed off as inevitable signs of aging. What if these are your client’s early warning system of deeper hormonal chaos already underway? In this episode of ReInvent Healthcare, Dr. Ritamarie sits down with hormone specialist and bestselling author Dr. Mariza Snyder to discuss t…
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How Fatty Liver Triggers Insulin Resistance, And What to Do About It
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12:22What if the first signs of metabolic breakdown aren’t in the pancreas or the blood sugar but hidden deep in the liver? In this episode of ReInvent Healthcare, Dr. Ritamarie takes you inside the metabolic feedback loop few practitioners are trained to detect. Long before glucose rises or A1C shifts, subtle signals in the liver may already be pointin…
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RLR MAIN PODCAST Episode description RR discuss a case of AKI Student discount https://www.rlrcpsolvers.com/student-discounts/ IMG discount Use coupon code RLRIMG at check out https://rlrcpsolvers.com/annual-planBy rabihgeha
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Episode 416 – Clinical Unknown Series with Dr. Vinicius de Sousa
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51:23https://clinicalproblemsolving.com/wp-content/uploads/2025/08/CUS-Aug-28-2025-final.wav In this episode of the Clinical Unknown Series, Noah and Vini will address a rash case presented by Mark and Debora. Mark will share his insights on the diagnosis by the end of the episode. Download CPSolvers App here RLRCPSOLVERS P.S.: DJ Noah will play “Xote d…
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Your Body’s Cry for Help: What Conventional Thyroid Testing Isn’t Telling You
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39:50What if your client’s labs show everything is “normal,” but their symptoms are screaming otherwise? In this episode of ReInvent Healthcare, Dr. Ritamarie sits down with holistic nutritionist and restorative wellness practitioner Divya Gupta to uncover the hidden truths behind thyroid dysfunction. Drawing from her own journey with Hashimoto’s and ga…
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Episode 415 – Spaced Learning Series – Beyond The Coagulation Cascade
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56:37https://clinicalproblemsolving.com/wp-content/uploads/2025/08/SLS-8-2025-RTP.mp3 Episode description: does your PTT cross the upper limit of normal when you think about the coagulation cascade? Got *mixed* feelings about APLS labs? This episode might be for you! Featuring: Valeria Roldan Jasdeep Bajwa Elena Storz Mukund Raguram Schemas Coagulopathy…
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Melatonin and Metabolic Health – The Nighttime Hormone That Shapes Your Metabolism
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10:50What if a key regulator of blood sugar, fat storage, and insulin sensitivity was hiding in plain sight, active only in the dark? In this episode of ReInvent Healthcare, Dr. Ritamarie explores one of the most overlooked hormonal players in metabolic function. It’s not a supplement, not a medication, and not a superfood, but it profoundly influences …
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Episode 414: Spaced Learning Series, dysuria
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35:01Tune in as Austin, Oumaima, Maryana and David discuss a patient with dysuria in an outpatient setting. https://clinicalproblemsolving.com/wp-content/uploads/2025/08/SLS-MORAD-6_22_25-0.mp3 Download CPSolvers App here RLRCPSOLVERS Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus…
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Episode 413: Rafael Medina Hepatology Episode with Dr. Tapper – Driver or Bystander
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44:10https://clinicalproblemsolving.com/wp-content/uploads/2025/08/HepatologyFinal.mp3 In this hepatology episode, Dr. Hirsh Elhence presents a case to Dr. Elliot Tapper. They discuss the question: “Is the liver the driver or a bystander?” Facilitator: Dr. Madellena (Maddy) Conte Case Presenter: Dr. Hirsh Elhence, current resident at University of Color…
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The Silent Language of the Body: Rethinking Chronic Illness, Pain, and Autoimmunity with Isabelle Amigues, MD
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25:50What if your patient’s persistent symptoms aren’t fully explained by labs, imaging, or even your best root-cause protocols? In this episode of ReInvent Healthcare, Dr. Ritamarie sits down with rheumatologist-turned-integrative-healer Dr. Isabelle Amigues to explore the deeper messages the body is trying to send—through pain, illness, and resistance…
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Episode 412: Schema Episode – Seizure, Fever, Encephalopathy
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42:06https://clinicalproblemsolving.com/wp-content/uploads/2025/08/SchemaEp_SeizuresFever_Final.mp3 Mark presents a case of seizures, fever, and meningoencephalitis to Youssef, Maddy, and Noah. Lymphocytic Pleocytosis Schema Seizures Schema To join us live on Virtual Morning Report (VMR), sign up HERE. Download CPSolvers App here RLRCPSOLVERS…
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The Real Reason Women Gain Weight in Midlife
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11:07If your clients are gaining weight in their 40s or 50s despite clean eating and regular movement, it’s not simply “aging” or “hormones.” In this episode of ReInvent Healthcare, Dr. Ritamarie explores a metabolic adaptation that occurs during midlife and alters how the body responds to glucose, insulin, and stress. There’s a multi-system shift that …
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Episode 411 – RLR – Abrupt Abdominal Pain
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30:08https://clinicalproblemsolving.com/wp-content/uploads/2025/08/Case-143-RLR.mp3 Episode description RR discuss abrupt abdominal pain, nausea and vomiting Student discount https://www.rlrcpsolvers.com/student-discounts/ IMG discount Use coupon code RLRIMG at check out https://rlrcpsolvers.com/annual-plan…
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