Gregory Austin and Dr. Chad Briscoe unzip, unlock, and uncover, the Stories Behind Medical Progress by sharing the latest and greatest advances in biopharmaceuticals and medical technologies in a fun, entertaining, and enlightening interview format. We bring on innovative leaders across the life sciences. The format is like a conversation you might overhear at the bar or at dinner after a day of great life science talks at a conference, engaging and accessible.
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Navigating Challenges in Drug Discovery with Dr. Alfred Botchway
51:52
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51:52In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Alfred Botchway, CEO of Attentive Science, to discuss his journey in biomedical science and the groundbreaking work being done at the intersection of AI, non-clinical safety, and drug discovery. Dr. Botchway shares his insights on the role of AI in refining t…
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In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe reflect on their journey over the past year, discussing key themes and insights gained from their guests. They explore the humanistic approach to healthcare, the impact of AI in drug development, common threads among successful individuals, personal growth through conver…
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Women in Pharmaceutical Sciences and their Allies with Dr. Ines Santos and Dr. Julie Sable
1:11:01
1:11:01
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1:11:01In this episode of BioTalk Unzipped, hosts Gregory Austin and Chad Briscoe welcome Dr. Ines Santos and Dr. Julia Sable to discuss their experiences and contributions in the pharmaceutical sciences, particularly focusing on women's roles in the field. The conversation covers their personal journeys into science, the importance of STEAMpark.org in ed…
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Are AI Doctors coming soon? A Discussion about AI in Medical Devices. - with Dr. Alex Friedman
1:10:29
1:10:29
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1:10:29In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe welcome Dr. Alex Friedman, a seasoned expert in regulatory affairs for medical devices and AI as Software as a Medical Device. Chapters 02:26 Introduction to BioTalk Unzipped 03:40 Charity Spotlight: Americares 05:01 Dr. Alex Friedman's Career Journey 11:52 The Regulator…
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Collaborating for Innovation: Biopharma Success with Dr. Nathan Teuscher
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31:39
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31:39In this episode of BioTalk Unzipped, hosts Gregory Austin and Chad Briscoe continue their conversation with Dr. Nathan Teuscher, a seasoned expert in clinical pharmacology and pharmacometrics. They discuss the challenges and opportunities presented by new technologies, particularly in drug development and patient engagement. The conversation highli…
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The Future of Pharmacometrics with Dr. Nathan Teuscher
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33:15In this episode of BioTalk Unzipped, hosts Gregory Austin and Chad Briscoe welcome Dr. Nathan Teuscher, a seasoned expert in clinical pharmacology and pharmacometrics. The conversation explores Nathan's career journey, the innovative charity Light the World, and the transformative role of AI in drug development. They discuss the challenges and oppo…
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Insights from AAPS PharmSci 360 Live with Dr. Mark Arnold
29:49
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29:49In this episode of BioTalk Unzipped, host Gregory Austin and co-host Chad Briscoe engage with Dr. Mark Arnold, a distinguished bioanalytical thought leader. They discuss the impact of recent FDA regulations on drug development, the importance of community support through the Samaritan Purse charity, especially on recent hurricane victims, and the e…
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Digital Twins: The Future of Drug Discovery with Dr. Tomáš Helikar
37:38
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37:38BioTalk Unzipped, hosts Gregory Austin and Chad Briscoe engage with Dr. Tomas Helikar in an exciting discussion on the future of AI, digital twins, and personalized medicine. From mathematical models and immune system simulations to groundbreaking collaborations with the Department of Defense, this episode uncovers how digital twins have the potent…
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Transforming Immunology: The Promise of Digital Twins with Dr. Tomáš Helikar
32:29
32:29
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32:29Dr. Tomas Helikar, a leading researcher in bioinformatics and systems biology, delves into groundbreaking work on developing a personalized immune digital twin, which aims to revolutionize the understanding and treatment of immune-related diseases. Chapters 00:00 Introduction to BioTalk Unzipped 01:50 Meet Dr. Tomas Helikar 04:34 The Journey into S…
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How AI is Transforming Drug Development: Reflections from AAPS - PharmSci 360 with Dr. Mark Arnold
36:11
36:11
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36:11Dr. Mark Arnold, a distinguished bioanalytical thought leader with an impressive track record in supporting drug development programs. Mark is the Owner and Principal at Bioanalytical Solution Integration, where he provides strategic counsel on complex bioanalytical assays and regulatory compliance. With over 35 years of experience, including leade…
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Biotech Funding Trends and the Rise of Digital Twinning with CEO Scott Ogle
29:40
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29:40EP-23. In the second half of this compelling conversation on BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe continue their deep dive with Scott Ogle, CEO of TruLab. They explore the surprising parallels between the banking and pharma industries, the game-changing role of digital twinning in clinical trials, and the biotech funding landscape.…
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Technology Meets Purpose: Transforming Clinical Trials at TruLab with CEO Scott Ogle
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33:37Summary In this 22nd episode of BioTalk Unzipped, host Gregory Austin and co-host Chad Briscoe engage with Scott Ogle, CEO of TrueLab, discussing his journey from finance to the pharmaceutical industry, the impact of personal experiences on innovation, and the importance of technology in clinical trials. They explore how to hire the best employees …
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Mentoring in Pharmaceutical Science with Dr. Jim Shen
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35:08Mentoring in Pharmaceutical Science with Dr. Jim Shen Summary In Episode 21 of BioTalk Unzipped, host Gregory Austin and co-host Dr. Chad Briscoe interview Dr. Jim Shen, the executive director and head of regulated bioanalysis operations at BMS. Jim discusses his early career in bioanalysis and the importance of mentorship. He emphasizes the need t…
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Great Advances in Cancer Research with Dr. Jim Shen
37:19
37:19
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37:19In this episode (EP20) of BioTalk Unzipped, host Gregory Austin and co-host Dr. Chad Briscoe interview Dr. Jim Shen, the Executive Director and Head of Regulated Bioanalysis Operations at BMS. They discuss topics such as the advancements in cancer therapies, the integration of AI and mechanistic modeling in drug development, and the complexities of…
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The Future of Hybrid Healthcare: Insights from Zealic CEO Chuck Piccirillo
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39:32
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39:32In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe continue their conversation with Zealic CEO, Chuck Piccirillo. They delve into the unique challenges of the patient journey and the increasing demand for hybrid healthcare solutions that offer more flexibility. The discussion highlights the rise of virtual health, particularly…
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Genetic Diagnostics & Student CEOs with Dr. Jonathon Hill
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33:17
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33:17Summary In this conversation, Dr. Jonathon Hill discusses the unique partnership between his lab and the university, which allows students to become entrepreneurs, develop their own projects, and become the CEO. Dr. Hill discusses the potential for AI to better diagnose disease based on the individual’s genome. He also talks about Lumicell's fluore…
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How AI is Helping Diagnose Disease with Chuck Piccirillo
38:04
38:04
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38:04Summary In this conversation, Gregory Austin and Chad Briscoe interview Chuck Piccirillo, CEO of Zealic Health, about his experience in the healthcare industry and the focus on patient-centric solutions. Chuck shares his personal journey with colitis and how it ultimately inspired him to start Zealic Health. The company aims to provide highly patie…
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Reptiles, Treatments, and Cell-Gene Therapy with Dr. Vick
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38:01Summary Dr. Andy Vick shares some of the things that surprised him throughout his career and he discusses his passion for reptiles and his experience discussing the pharmaceutical potential of venom with future toxicologists at Ashland University. Next, Andrew Vick discusses his role as an adjunct professor at Ohio State University, his involvement…
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Amyloidosis Exposed: New Hope with Dr. Vick
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40:52
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40:52Summary Dr. Andy Vick discusses his work at Attralus Therapeutics, a biotech company focused on developing treatments for systemic amyloidosis. He explains the etiology of the disease and how Attralus is attacking it using therapeutic antibodies with a pan amyloid reactive peptide sequence. The company is also developing a diagnostic tool to visual…
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A Diagnostic Breakthrough for Alzheimer’s with Dr. Jonathon Hill
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30:25A Diagnostic Breakthrough for Alzheimer’s Summary In this conversation, Dr. Jonathan Hill discusses his work in nanopore sequencing-based technology and its applications in genetic and epigenetic research. He shares his experiences working in Brazil and his passion for preserving the rainforest. The conversation also explores the use of AI in analy…
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The AI Prescription: Revolutionizing Pharma & Patient Care with Jason Burke
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35:59
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35:59The AI Prescription: Revolutionizing Pharma & Patient Care with Jason Burke Summary In Episode 13, Jason Burke discusses the unique approach of the Duke program in providing real-world healthcare data to students. He also highlights the breakthrough in AI-generated drug discovery and its potential impact on investors and startups. The process of as…
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Unlocking the Future of Healthcare with Organoids, AI, and Quantum Computing with Jason Burke
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34:40
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34:40Summary In this episode of BioTalk Unzipped, the hosts discuss the applications and ethical concerns surrounding organoids, which are 3D cell clusters that mimic the features of full-sized organs. They explore the potential of brain organoids in brain-computer interfaces and neuroplasticity. The conversation then shifts to the impact of AI and data…
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Breakthrough in Melanoma, Rare Diseases, and Curative Therapies with Scott Schliebner
36:44
36:44
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36:44Summary In this episode, Scott Schliebner discusses the unique challenges and complexities of rare disease trials. He highlights the difficulties in recruiting patients, the multidisciplinary nature of care, and the importance of collaboration among various stakeholders. The role of AI in rare disease trials is also explored, with a focus on its po…
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Impact of AI in Rare Disease Trials with Scott Schliebner
36:12
36:12
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36:12Impact of AI in Rare Disease Trials with Scott Schliebner Summary In this episode, the hosts welcome Scott Schliebner as their guest and kick off with a charitable act, donating to Rare Givers. They delve into the Epitomee weight loss capsule's potential impact, then shift to discussing the challenges of establishing a North American infrastructure…
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Invaluable Lessons in Leadership and Science with Dr. Russell Grant
43:28
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43:28Description: In Episode 8 of BioTalk Unzipped, we dive deep into the scientific mind of Dr. Russell Grant, exploring how he navigates groundbreaking publications with a healthy dose of skepticism. From microsampling blood spots to dissecting experimental execution gaps, Dr. Grant reveals his strategies for separating scientific sizzle from substanc…
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Revolutionizing Diagnostic Patient Care with Dr. Russell Grant
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33:04Join us for Episode 7 of our podcast as we delve into the fascinating journey of Dr. Russell Grant, from the UK to America, navigating through large pharma to the field of diagnostics. Discover the nuances between bioanalytical approaches in clinical trials versus clinical healthcare, and Russ's insights on GLP environments. Learn how Russ tackled …
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False Positives In The AI Explosion with Dr. Stephanie Pasas Farmer
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33:56Welcome to Episode 6 of our podcast featuring Dr. Stephanie Pasas Farmer! 🎙️ Join us as we delve into the intricate world of data integrity, unveiling new software tools and the transformative impact they bring. Discover how virtual audits post-COVID, coupled with cloud security measures, are reshaping the landscape. 🔍 Explore the regulatory challe…
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How To Start A Company In Bioanalysis with Dr. Stephanie Pasas Farmer
27:35
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27:35🎙️ Episode 5 of BioTalk Unzipped is here! Join hosts Gregory Austin and Dr. Chad Briscoe as they chat with Dr. Stephanie Pasas Farmer, founder of Ariadne Software and BioData Solutions. Explore the origins of Stephanie's companies, and the creation of RedThread, an AI-Enabled Auditing Tool that blends human intelligence with AI. 🧠 Dive into the pra…
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Sickle Cell Breakthrough and Heartbreaking Stories with Dr. Russ Weiner
35:47
35:47
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35:47In Episode 4, (Part 2 of our conversation with Dr. Russ Weiner - a top scientific leader at Takeda), we boldly explore the Cell and Gene Therapy Industry, questioning its trajectory and potential impact on insurance companies. Shifting focus, we delve into a groundbreaking Sickle Cell Therapy breakthrough, discussing its triumphs, challenges, and t…
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Miraculous Cures: From Hospice to Survivor with Dr. Russ Weiner
36:54
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36:54In Episode 3 of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe dive deep into the world of biotech with an exclusive interview featuring the esteemed Dr. Russ Weiner. As a senior-level biopharmaceutical professional with over 30 years of hands-on experience, Dr. Weiner shares invaluable insights into pharmaceutical and biologic drug di…
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Science is NOT a Conspiracy Theory with Dr. Chad Briscoe & Gregory Austin
26:01
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26:01Welcome to another engaging episode of "BioTalk Unzipped" – the podcast where we unravel the fascinating world of biotechnology and drug discovery and unzip the stories behind medical progress. In Episode 2, we delve into the heart of the matter, exploring the new and painful challenges faced in the realm of drug discovery and development, as well …
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Cheers to Science: The BioTalk Unzipped Vision (Trailer)
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0:45Dr. Chad Briscoe Unveils the Vision - When Bar Conversations Meet Scientific Breakthroughs. Bringing great pharmaceutical science to the people in a light, fun, and inspirational manner. #biotechnology #pharmaceutical #science #drugdevelopment #drugdiscovery #researchBy BioTalk Unzipped
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The BioTalk Unzipped Premiere: Why Biotech Companies Fail
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25:22Welcome to the premiere of BioTalk Unzipped, the podcast where the complex world of biotechnology gets unzipped by your hosts, Gregory Austin and Dr. Chad Briscoe. In this inaugural episode, we invite you to pull up a virtual chair and join us in an enlightening conversation that transcends the boundaries of traditional scientific discussions. What…
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