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Applied Data Science Partners Podcasts

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At this moment of inflection in technology, co-hosts Elad Gil and Sarah Guo talk to the world's leading AI engineers, researchers and founders about the biggest questions: How far away is AGI? What markets are at risk for disruption? How will commerce, culture, and society change? What’s happening in state-of-the-art in research? “No Priors” is your guide to the AI revolution. Email feedback to [email protected]. Sarah Guo is a startup investor and the founder of Conviction, an investment f ...
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The AI Canvas

Applied Data Science Partners

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"The AI Canvas" delves into the remarkable potential of generative AI, and how it is impacting businesses and the arts in profound ways. Immerse yourself in enlightening fireside chats, captivating case studies, and revolutionary ideas as we unveil how AI is transforming industries, optimising operations, and redefining the creative realm with limitless possibilities.
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Project Geospatial

Project Geospatial

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Project Geospatial is a non-profit media organization committed to growth, innovation and collaboration among academic, commercial and government partners in the geospatial industry. We believe a revolution is coming in geospatial technology – big data is democratizing, satellites are shrinking, and the science of where has never been more important to the health and future of our planet. We provide a leading voice in geospatial industry trends, insights and cross-industry applications to he ...
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Cloudflare has spent nearly fifteen years making the Internet faster, more reliable, and more secure. So now that AI systems are changing the way we interact with the Internet, Cloudflare wants to help level the playing field for content creators. Sarah Guo and Elad Gil sit down with Matthew Prince, co-founder and CEO of Cloudflare to discuss the e…
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Sriram Krishnan was never interested in policy. But after seeing a gap in AI knowledge at senior levels of government, he decided to lend his expertise to the tech-friendly Trump administration. Senior White House Policy Advisor on AI Sriram Krishnan joins Elad Gil and Sarah Guo to talk about America’s AI Action Plan, a recent executive order that …
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In the generative AI revolution, quality data is a valuable commodity. But not all data is created equally. Sarah Guo and Elad Gil sit down with SurgeAI founder and CEO Edwin Chen to discuss the meaning and importance of quality human data. Edwin talks about why he bootstrapped Surge instead of raising venture funds, the importance of scalable over…
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Superintelligence, at least in an academic sense, has already been achieved. But Misha Laskin thinks that the next step towards artificial superintelligence, or ASI, should look both more user and problem-focused. ReflectionAI co-founder and CEO Misha Laskin joins Sarah Guo to introduce Asimov, their new code comprehension agent built on reinforcem…
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As a three-time founder, Parker Conrad has one piece of advice for aspiring entrepreneurs—don’t do it. The Rippling co-founder and CEO joins Sarah Guo to talk about what he learned from the crash at Zenefits, why most advice to founders is wrong, and how building a real platform—not a point solution—is the only way to win in SaaS. The two get into …
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AI has already fueled breakthroughs in biotechnology—but now, further advances in AI are poised to fuel pharmaceutical discoveries as well. Sarah Guo sits down with Joshua Meier and Jack Dent, co-founders of Chai Discovery, whose newly launched Chai-2 designs bespoke antibodies that bind to their targets at a jaw-dropping 20% rate. Jack and Joshua …
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Much of the scientific process involves searching. But rather than continue to rely on the luck of discovery, Google DeepMind has engineered a more efficient AI agent that mines complex spaces to facilitate scientific breakthroughs. Sarah Guo speaks with Pushmeet Kohli, VP of Science and Strategic Initiatives, and research scientist Matej Balog at …
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When will fully autonomous vehicles see widespread adoption? According to Applied Intuition, that future is closer than you may think. Applied Intuition’s CEO, Qasar Younis, and CTO, Peter Ludwig, talk with Elad Gil about how now is the best time to both work on self-driving vehicle technology and monetize it. Qasar and Peter discuss the advantages…
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What happens when you give AI researchers unlimited compute and tell them to compete for the highest usage rates? Ben Mann, Co-Founder, from Anthropic sits down with Sarah Guo and Elad Gil to explain how Claude 4 went from "reward hacking" to efficiently completing tasks and how they're racing to solve AI safety before deploying computer-controllin…
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In this episode of No Priors, Sarah and Elad are joined by Dr. Fei-Fei Li, AI pioneer, co-director of Stanford’s Human-Centered AI Institute, and founder of World Labs. Fei-Fei shares why she’s building at the intersection of embodiment and intelligence, and what today’s AI systems are still missing. From the early days of ImageNet to her vision fo…
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In this episode of No Priors, Sarah and Elad unpack the current state of the AI market - whether it’s consolidating, what’s enabling or blocking key mergers, and where the most promising untapped opportunities lie, particularly in biotech. They also explore the rise of world models and how AI’s novel methods for understanding complex systems may ul…
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Arvind Jain joins Sarah and Elad on this episode of No Priors. Arvind is the founder and CEO of Glean, an AI-powered enterprise search platform. He previously co-founded Rubrik and spent over a decade as an engineering leader at Google. In this episode, Arvind shares how LLMs are transforming enterprise search, why most tools in the space have fail…
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On this episode of No Priors, Sarah talks to Luis von Ahn, founder and CEO of Duolingo, the world’s most popular education app with over 116 million monthly users and a market cap of approximately $17 billion. Controversially, it has recently committed to being “AI-first.” They discuss why motivation is the biggest challenge in education, how Duoli…
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This week on No Priors, Elad and Sarah sit down with Eric Mitchell and Brandon McKinzie, two of the minds behind OpenAI’s O3 model. They discuss what makes O3 unique, including its focus on reasoning, the role of reinforcement learning, and how tool use enables more powerful interactions. The conversation explores the unification of model capabilit…
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On this episode of No Priors, Sarah sits down with Isa Fulford, one of the masterminds behind deep research. They unpack how the initiative began, the role of human expert data, and what it takes to build agents with real-world capability and even taste. Isa shares the differences between deep research and OpenAI’s o3 model, the challenges around l…
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This week on No Priors, Sarah and Elad are joined by Josh Goldman, cofounder and president of KoBold Metals. KoBold is using AI to transform how we discover critical minerals like lithium and cobalt, making the exploration process faster, more precise, and more scalable than traditional methods. In this episode, Josh explains how KoBold is rethinki…
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On this episode of No Priors, Sarah and Elad sit down with Brendan Foody, CEO and cofounder of Mercor, to discuss the company’s rapid growth and their vision for the future of the labor market. They dive into how AI is reshaping the workforce in real, tangible ways and what skills are worth investing in today. Brendan shares insights on evaluating …
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In this episode of No Priors, Sarah and Elad examine the current state of AI. They break down the recent dip in public markets, how tariffs could impact the tech industry, and where opportunities remain in large language models. They highlight the opportunities in more specialized models, new approaches to model development, and how the market is b…
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In this episode of No Priors, Elad and Sarah chat with Shiv Rao, MD, founder and CEO of Abridge. They dive into how Abridge is reshaping healthcare by creating AI tools that enhance clinical documentation and improve doctor-patient interactions. Shiv shares his thoughts on building trust with established healthcare systems, giving agency and time b…
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This week on No Priors, Elad speaks with Chelsea Finn, cofounder of Physical Intelligence and currently Associate Professor at Stanford, leading the Intelligence through Learning and Interaction Lab. They dive into how robots learn, the challenges of training AI models for the physical world, and the importance of diverse data in reaching generaliz…
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This week on No Priors, Sarah and Elad talk with GitHub CEO Thomas Dohmke about the rise of AI-powered software development and the success of Copilot. They discuss how Copilot is reshaping the developer workflow, GitHub’s new Agent Mode, and competition in the developer tooling market. They also explore how AI-driven coding impacts software pricin…
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This week on No Priors, Sarah is joined by Dan Hendrycks, director of the Center of AI Safety. Dan serves as an advisor to xAI and Scale AI. He is a longtime AI researcher, publisher of interesting AI evals such as "Humanity's Last Exam," and co-author of a new paper on National Security "Superintelligence Strategy" along with Scale founder-CEO Ale…
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This week on No Priors, Sarah sits down with Noubar Afeyan, Co-founder and CEO of Flagship Pioneering, the biotech firm behind groundbreaking companies like Moderna. They explore how Flagship creates the conditions for scientific breakthroughs, tackles regulatory uncertainty, and pushes the boundaries of discovery. Noubar shares insights on AI’s ro…
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On this week’s episode of No Priors, Sarah Guo is joined by leading members of the teams at Vevo Therapeutics and the Arc Institute – Nima Alidoust, CEO/Co-Founder at Vevo Therapeutics; Johnny Yu, CSO/Co-Founder at Vevo Therapeutics; Patrick Hsu, CEO/Co-Founder at Arc Institute; Dave Burke, CTO at Arc Institute; and Hani Goodarzi, Core Investigator…
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Kyle Vogt joins Sarah and Elad on this week’s episode of No Priors. A serial entrepreneur, Kyle co-founded Twitch, transforming live streaming, and later Cruise, the autonomous vehicle company acquired by GM for $1 billion. Now he’s taking on AI-powered home robotics with The Bot Company. In this episode, Kyle shares his journey building transforma…
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This week on No Priors, Sarah sits down with Harvey cofounder and CEO Winston Weinberg. Harvey is one of the leading application layer AI companies, building domain-specific AI for law firms, professional service providers, and the Fortune 500. They are already working with companies like Bridgewater, KKR, PWC, and O’Melveny with over $500M in fund…
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The segment provides a broad understanding of theCivil Applications Committee (CAC), which serves as a crucial link between different sectors to facilitate the use of advanced technologies for various public benefits. It highlights the CAC's role inenabling federal civil agencies to access and utilize remote sensing data and capabilities from theIn…
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This week on No Priors, Sarah and Elad celebrate the 100th episode! They dive into the biggest AI stories of 2025, breaking down DeepSeek—truth vs. hype, the rapid consumer adoption, and the real cost of training the models. They debate model commoditization and the value of being a frontier model provider vs. building on existing work. Plus, they …
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This week on No Priors, Elad sits down with Rick Caruso, LA real estate developer and runner-up in the 2022 mayoral race. With experience serving under three LA mayors, as well as on the police commission and the board of water and power, Rick offers a unique perspective on the systemic failures that contributed to the devastation of the January 20…
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This week on No Priors, Sarah and Elad sit down with Bill Clerico, founder of Convective Capital, an early stage venture fund focused on technology-driven solutions for wildfire mitigation and climate resilience. The wildfires in Los Angeles have caused unprecedented property damage and immense hardship for countless individuals and families. This …
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In this episode, Project Geospatial explores the USGS Landsat year in review.Landsat, a satellite program capturing Earth images for over 50 years, is invaluable for monitoring environmental changes and managing resources. The program’s recent report highlights its worth at $25.6 billion, showcasing its significant real-world benefits, such as impr…
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Today on No Priors, co-founder and CEO of Decagon, Jesse Zhang, joins Elad to discuss the future of agentic customer support. Decagon provides AI-powered customer interactions for companies like Rippling, Notion, Duolingo, Classpass, Substack, Vanta, Eventbrite, and more. Jesse shares the thesis behind starting Decagon, why he sees customer support…
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SummaryThe Geography 2050 Symposium highlighted significant themes surrounding climate change, conflict, human mobility, technology, and collaboration. Experts gathered to discuss the complexities of climate as a “threat multiplier” and its impact on migration and societal issues.Highlights🌍 Climate change is a “threat multiplier” affecting resourc…
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Project Geospatial presents an AI experiment aggregating and analyzing our content captured from FedGeoDay 2024. Not all content is covered but this definitely covers the highlights and major themes of the conference.Get ready for a deep dive into a recap pf key discussions and innovative ideas presented at FedGeoDay 2024! This recap podcast explor…
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SummaryThe video recaps the 2024 FOSS4G North America event, highlighting key discussions and innovations in open-source geospatial technology.Highlights Overview of the FOSS4G NA event, focusing on open-source geospatial advancements. Insightful discussions on collaborative projects and community contributions. Presentations from industry leaders …
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Here's a podcast description for our GEOINT 2024 recap episode, highlighting major themes from the conference. This is an AI podcast experiment aggregating our content helping analyze and bring focus on what's important. Tune in and listen in.Join us for a deep dive into the highlights of the GEOINT 2024 Symposium! This year's conference in Orlando…
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Today on No Priors, Elad chats with Erik Bernhardsson, founder and CEO of Modal Labs, a platform simplifying ML workflows by providing a serverless infrastructure designed to streamline deployment, scaling, and development for AI engineers. Erik talks about his early work on Spotify’s ML algorithms, what Modal offers today, and his vision for build…
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From above the clouds to boots on the ground, how is geospatial technology revolutionizing disaster response and recovery?In this episode of Project Geospatial's Industry Limelight, we sit down with Piers Dormeyer, CEO of EagleView, a leader in geospatial technology that's changing the way we understand and interact with the world around us.Piers, …
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2024 has been a year of transformative technological progress, marked by conversations that have reshaped our understanding of AI's evolution and what lies ahead. Throughout the year, Sarah and Elad have had the privilege of speaking with some of the brightest minds in the field. As we look back on the past months, we’re excited to share highlights…
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Today on No Priors, Sarah sits down with Elias Torres, CEO and founder of Agency, an AI agent for customer success teams. Elias shares his journey from growing up in Nicaragua to founding several companies, leading engineering at HubSpot, and selling Drift for $1B. He also discusses his work consulting with OpenAI in 2022, which deepened his unders…
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In this episode of No Priors, Sarah sits down with Felix Ejeckam and Ty Mitchell, founders of Akash Systems, a company pioneering diamond-based cooling technology for semiconductors used in space applications and large-scale AI data centers. Felix and Ty discuss how their backgrounds in materials science led them to tackle one of the most pressing …
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In this episode of No Priors, Sarah talks with Eric Simons, co-founder and CEO of StackBlitz. The company has experienced explosive growth since the launch 2 months ago of Bolt.new, an AI application that lets users prompt, run, edit, and deploy full-stack applications directly in the browser. Eric talks about the years-long journey that led to ove…
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In this episode of No Priors, Sarah is joined by Aidan Gomez, cofounder and CEO of Cohere. Aidan reflects on his journey to co-authoring the groundbreaking 2017 paper, “Attention is All You Need,” during his internship, and shares his motivations for building Cohere, which delivers AI-powered language models and solutions for businesses. The discus…
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In this week’s episode of No Priors, Sarah and Elad sit down with the Google DeepMind team behind AlphaProof, Laurent Sartran, Rishi Mehta, and Thomas Hubert. AlphaProof is a new reinforcement learning-based system for formal math reasoning that recently reached a silver-medal standard in solving International Mathematical Olympiad problems. They d…
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In this week’s episode of No Priors, Sarah and Elad sit down with Jensen Huang, CEO of NVIDIA, for the second time to reflect on the company’s extraordinary growth over the past year. Jensen discusses AI’s takeover of datacenters and NVIDIA’s rapid development of x.AI’s supercluster. The conversation also covers Nvidia’s decade-long infrastructure …
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In this week’s episode of No Priors, Sarah sits down with Tarek Mansour, CEO of Kalshi—the first CFTC-regulated prediction market exchange in the U.S. They dive into Kalshi’s recent victory to legalize election betting, explore ethical questions around trading on elections, and discuss whether prediction markets can offer more accuracy than traditi…
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Qiusheng Wu’s presentation on Leafmap at FOSS4G NA 2024 highlights its capabilities for interactive geospatial data visualization using Python. Leafmap simplifies data access and mapping tasks, making it ideal for users at all skill levels.Highlights🌐 Leafmap allows browser-based geospatial data visualization without the need for desktop software.🐍…
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Jason Gilman from Element 84 discusses the integration of large language models (LLMs) with geospatial data to enhance search and analysis capabilities in his talk at FOSS4G NA 2024.Highlights🌍 LLMs can bridge the gap between geospatial data and user inquiries, enabling effective search.🤖 LLMs function like CPUs, processing natural language but lac…
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The presentation by Jonathan Mason and Jian Wu discusses the use of unmanned surface vehicles (USVs), specifically sail drones, for tracking vessels at sea. It highlights the unique challenges of ocean exploration and monitoring, and how sail drones, powered by wind and solar energy, enable efficient data collection for various applications includi…
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Nicholas Knize discusses optimizing geospatial indexing and hybrid search using advanced data structures within the Lucene framework at FOSS4G NA 2024. He emphasizes reducing cloud infrastructure waste and improving geospatial data processing efficiency.Highlights🌍 Discusses hybrid search and GeoAI advancements.💡 Explains the evolution of geospatia…
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