Best Angina Podcasts (2025)

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Understanding Angina Symptom Trajectories After Invasive vs. Conservative Treatment | JACC Deep Dive 8:00

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17d ago8:00

8:00

In this JACC Deep Dive, Dr. Harlan Krumholz highlights a study by Ikemura et al. that used data from the ISCHEMIA trial to model how angina symptoms evolve over three years in patients with stable coronary disease treated either invasively or conservatively. The study identified six distinct symptom trajectories, showing that while most patients im…

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Mendelian Randomisation in Cardiovascular Research - Assumptions, Pitfalls & Practice 28:22

8h ago28:22

28:22

Send us a text Host Pablo Perel and co-host Prof. Raul Santos talk with Dr Jiao Luo about Mendelian randomisation (MR) in cardiovascular research, what it is, core assumptions (relevance, independence, no horizontal pleiotropy), common pitfalls (weak instruments, population mismatch, non-linearity), and how to read MR papers. The episode references…

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Percutaneous Mechanical Aspiration: A New Frontier in Endocarditis Care | JACC Deep Dive 7:15

12d ago7:15

7:15

In this episode of JACC Deep Dive, Editor-in-Chief Dr. Harlan Krumholz explores groundbreaking findings from the CLEAR-IE registry—the largest study to date on percutaneous mechanical aspiration (PMA) for right-sided infective endocarditis. He discusses the procedure’s feasibility, outcomes, and its role alongside surgery, offering insights into ho…

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Ep. 33 - Two Little-Known Tests That Could Save Your Life 16:52

16d ago16:52

16:52

Welcome to Cardiovascular Matters! In this episode, Dr. Craig Walker and Terry Roberts explain the vital role of coronary calcium scores in assessing your heart disease risk. Dr. Walker discusses: ✔ What the coronary calcium score test measures and why it's important. ✔ How calcium buildup relates directly to heart disease risk. ✔ Who should consid…

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Tirzepatide in HFpEF and Obesity: Consistent Benefits Regardless of Diabetes Status | JACC Deep Dive 11:54

22d ago11:54

11:54

In this JACC Deep Dive, Dr. Harlan Krumholz discusses a pre-specified analysis from the SUMMIT trial, which evaluated the effects of tirzepatide in patients with heart failure with preserved ejection fraction (HFpEF) and obesity, both with and without type 2 diabetes. The study found that tirzepatide significantly improved symptoms, function, and r…

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Ep. 32 - The Truth About Weight Loss Injections and Heart Disease Prevention 23:52

1M ago23:52

23:52

Welcome to Cardiovascular Matters! Join Dr. Craig Walker and Terry Roberts as they discuss groundbreaking new medications revolutionizing cardiovascular treatment. In this episode, you'll learn about: ✔ The latest FDA-approved medications for cardiovascular disease prevention. ✔ How these drugs effectively manage cholesterol and diabetes. ✔ Reducin…

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Environmental Exposure as Intervention: HEPA Filtration and Blood Pressure Near Traffic Corridors | JACC Deep Dive 8:15

1M ago8:15

8:15

In this Deep Dive, Editor-in-Chief Dr. Harlan Krumholz explores a pragmatic, randomized crossover trial testing whether in-home HEPA filtration can reduce blood pressure in adults living near high-traffic roadways. The findings offer early insights into how targeted environmental interventions may influence cardiovascular risk—especially among indi…

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Ep. 31 - Women and Microvascular Disease: The Hidden Heart Threat 19:19

2M ago19:19

19:19

Welcome to Cardiovascular Matters! In this episode, Dr. Craig Walker and Terry Roberts shed light on microvascular heart disease, a condition that affects many women — and is often overlooked or misdiagnosed. Dr. Walker explains: ✔ What microvascular disease is and how it differs from large vessel heart disease. ✔ Why women are more frequently affe…

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Master DAPT | JACC Deep Dive 7:28

2M ago7:28

7:28

In this episode of JACC Deep Dive, Dr. Harlan Krumholz explores new insights from a post hoc analysis of the MASTER DAPT trial, highlighting the real-world burden of ischemic and bleeding events in high bleeding risk patients after PCI. By examining recurrent—not just first—events, the study sheds light on how abbreviated dual antiplatelet therapy …

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Cardiac Biomarkers in ATTR-CM From HELIOS-B | JACC Deep Dive 7:01

2M ago7:01

7:01

In this episode of JACC Deep Dive, KACC Editor-in-Chief Harlan M. Krumholz, MD, SM, FACC, explores a post hoc analysis of the HELIOS-B trial, which examined whether echocardiographic parameters can track treatment response in transthyretin amyloid cardiomyopathy (ATTR-CM) patients treated with vutrisiran. The study found that changes in cardiac fun…

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Insights From the INTERASPIRE Study | JACC Deep Dive 10:56

2M ago10:56

10:56

JACC focuses in again on Lipids in our June 3 issue, bringing critical insights into emerging targeted therapies. In the June 3 Deep Dive, editor-in-chief Harlan M. Krumholz, MD, SM, FACC, reviews the INTERASPIRE study by Ray et al, reviewing implications, key findings, and a thoughtful summary and analysis of the reviewer findings.…

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Vutrisiran Impact on Functional Capacity and QOL | JACC Deep Dive | JACC 8:25

2M ago8:25

8:25

Go behind the scenes with JACC as editor-in-chief Harlan M. Krumholz, MD, SM, FACC, talks about what 's caught his attention in the latest JACC issue on amyloid. In this paper by Sheikh et al, the authors did a pre-specified exploratory analysis from the HELIOS-B trial, evaluating vutrisiran in patients with transthyretin amyloid cardiomyopathy (AT…

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Individual Variation in Tirzepatide Response | JACC Deep Dive 8:19

2M ago8:19

8:19

Join JACC Editor in Chief Harlan Krumholz, MD, SM, as he speaks about this ACC.25 presentation published in JACC. This fascinating study by Rohan Khera et al independently analyzed patient-level data from the SURMOUNT trials of tirzepatide for obesity. The study revealed striking individual variability in weight loss and metabolic response, even to…

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Revisiting the SUMMIT Trial | JACC Deep Dive 5:55

2M ago5:55

5:55

This JACC Deep Dive in our May 13 issue highlights new findings from the SUMMIT CKD study, showing that terzepatide improves symptoms, function, and weight in patients with HFpEF and obesity—regardless of kidney function. The analysis also underscores the importance of using both creatinine and cystatin C to better assess kidney health. Reviewers p…

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1-Year Results of ADVANTAGE AF | JACC Deep Dive 7:28

2M ago7:28

7:28

In this JACC Deep Dive episode, Dr. Harlan Krumholz reviews the ADVANTAGE-AF trial, which evaluated pulse field ablation (PFA) as a treatment for persistent atrial fibrillation. The study demonstrated that PFA is a safe and effective approach, with strong symptomatic outcomes and a low complication rate, though questions remain about long-term dura…

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Disentangling the Impact of Adiposity From Insulin Resistance in HFpEF | JACC Deep Dive 6:19

2M ago6:19

6:19

In a Deep Dive in our May 13 issue, Editor-in-Chief Harlan Krumholz, MD, SM, FACC, discusses a study led by Barry Borlaug that investigates whether excess weight or metabolic dysfunction has a greater impact on heart failure with preserved ejection fraction (HFpEF). The findings showed that obesity—more than insulin resistance—was strongly associat…

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Sudden Cardiac Arrest in Young Athletes | JACC Deep Dive 6:02

2M ago6:02

6:02

In this JACC Deep Dive episode, Editor-in-Chief Dr. Harlan Krumholz discusses a major study on sudden cardiac arrest in young competitive athletes, highlighting survival rates, causes, and racial disparities. The study shows that survival improves dramatically with immediate AED use and has increased over time, emphasizing the need for widespread e…

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Altshock-2 | JACC Deep Dive 8:25

2M ago8:25

8:25

In this in-depth analysis of the Altshock-2 trial (Study on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic Shock), Harlan M Krumholz, MD, FACC, goes deep into the study and its two related editorials. Listen here for this unique behind-the-scenes look at the review process, plus a thoughtfu…

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Epidemiology and Outcomes in HFimpEF | JACC Deep Dive 8:31

2M ago8:31

8:31

In this JACC Deep Dive, Editor-in-Chief Harlan M. Krumholz, MD, SM, discusses a large real-world study by Min et al. examining heart failure with improved ejection fraction (HFimpEF) in over 24,000 patients. The study found that while EF improvement is common (30%), true remission is rare and relapse occurs in about 25% of cases—highlighting the ne…

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Global Heart Podcast: Field Lessons from Ethiopia - Real World Insights in Hypertension Care 33:50

2M ago33:50

33:50

Send us a text In this episode, host Pablo Perel speaks with Mr. Girma Dessie and Dr. Andrew Moran about a powerful example of real-world cardiovascular implementation research from Ethiopia. Mr. Dessie presents a recent study investigating why patients enrolled in a hypertension program were missing follow-up visits, despite strong program support…

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ACURATE neo2 Under-Expansion | JACC Deep Dive 15:11

2M ago15:11

15:11

JACC's July 29 issue explores why the ACURATE neo2 valve failed in its IDE trial, with a post-hoc analysis pointing to under-expansion in heavily calcified anatomies as a potential culprit. Though the valve is off the market, the findings raise critical questions about procedural success, device design, and future innovation in TAVR. Listen to our …

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Validation of AHA PREVENT in Healthcare Populations | JACC Deep Dive 6:29

3M ago6:29

6:29

In this JACC Deep Dive, JACC Editor in Chief Harlan M. Krumholz, MD, SM, explores a study led by Dr. Pradeep Natarajan that evaluates how well the new AHA PREVENT risk equations predict cardiovascular events across four major U.S. health systems. The study found wide variation in performance—PREVENT was well-calibrated at Penn Medicine but signific…

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Plaque Vulnerability and Risk Factors | JACC Deep Dive 5:38

3M ago5:38

5:38

In this JACC Deep Dive, Harlan M. Krumholz, MD, SM, FACC reviews a study by Covani, et al that uses OCT imaging in over 1,500 ACS patients to show how increasing cardiovascular risk factor burden—like smoking, diabetes, and hypertension—is strongly associated with vulnerable plaque features such as thin caps, inflammation, and rupture. The findings…

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IHCA Incidence Rates | JACC Deep Dive 6:28

3M ago6:28

6:28

In this JACC Deep Dive, Harlan M. Krumholz, MD, SM, FACC, discusses a new study in the July 8 issue of JACC, authored by Saket Girotra MD, SM, et al. In the study, which links national registry and Medicare data, the authors found striking hospital-level variation in cardiac arrest rates and outcomes—and identified better nurse staffing as a key fa…

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Conversations from the Heart: Living with Angina 31:36

3M ago31:36

31:36

Send us a text This episode is hosted by Sean Taylor, Director of Science and Public Health at the World Heart Federation, and Shreya Shrikhande, Science and Public Health Officer in the same team. They speak with two patients, Maria and Chandrima, who share their personal journeys with angina. Although their experiences are different—one facing ye…

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Ep. 30 - Early Detection of Peripheral Vascular Disease: Why It Matters 22:05

4M ago22:05

22:05

Welcome to Cardiovascular Matters! In this episode, Dr. Craig Walker and Terry Roberts dive into peripheral artery disease (PAD), a widespread yet frequently unnoticed condition that significantly increases the risk of heart attack, stroke, and amputation. Peripheral artery disease can silently progress without noticeable symptoms, especially in ol…

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Global Heart Podcast: Launching World Heart Report 2025 31:03

4M ago31:03

31:03

Send us a text In this episode, we explore the key findings of the World Heart Report 2025, which focuses on obesity and cardiovascular disease. The report’s lead authors, Professor Mariachiara Di Cesare from the University of Essex and Professor Francisco Lopez-Jimenez from the Mayo Clinic, delve into why obesity remains one of the most neglected …

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Ep. 29 - When is it Too Late? Restoring Blood Flow in Critical Limb Ischemia 19:39

4M ago19:39

19:39

Welcome to Cardiovascular Matters! In this episode, Dr. Craig Walker and Terry Roberts tackle the serious condition known as critical limb ischemia (CLI), a leading cause of limb amputation. Critical limb ischemia occurs when blockages severely reduce blood flow to the legs, causing pain, ulcers, and gangrene. Dr. Walker shares: ✔ How to recognize …

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Ep. 28 - Pelvic Congestion Syndrome: Unraveling the Mysteries 14:18

5M ago14:18

14:18

Welcome to Cardiovascular Matters! In this episode, Dr. Craig Walker and Terry Roberts discuss pelvic congestion syndrome, a condition that significantly impacts the quality of life but is frequently misunderstood and misdiagnosed. Pelvic congestion syndrome involves the improper drainage of blood through the veins in the pelvis, leading to various…

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Ep. 27 - Beyond the Angiogram: Understanding Small Vessel Disease in Women and Men 19:22

6M ago19:22

19:22

Welcome to Cardiovascular Matters! In this episode, Dr. Craig Walker and Terry Roberts delve into the topic of small vessel disease, an often overlooked condition that affects more women than men but is crucial to understand for both. Small vessel disease can lead to serious cardiovascular events due to the obstruction of the smallest blood vessels…

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Global Heart Podcast: 2025 WHO Guidelines on Low Sodium Salt Substitutes 48:10

6M ago48:10

48:10

Send us a text In this episode, we explore the 2025 WHO guidelines on the use of low-sodium salt substitutes. Prof. Mary L’Abbé, a member of the WHO guideline development group, explains the evidence, recommendations, and key considerations behind this important new guideline. Later, Prof. Jaime Miranda reflects on the global public health implicat…

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Ep. 26 - How Early Cardiovascular Evaluation Can Save Your Life! 28:11

6M ago28:11

28:11

Welcome to Cardiovascular Matters! In this episode, Dr. Craig Walker and Terry Roberts discuss one of the most common yet crucial questions: When should you go in for a cardiovascular checkup? Heart disease remains the #1 cause of death, but early detection can save lives. Dr. Walker explains: ✔ Who is at highest risk for heart disease. ✔ The 5 maj…

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Ep. 25 - Breakthrough Treatment for Sleep Apnea: GLP-1 Agonists 19:33

7M ago19:33

19:33

Discover how a groundbreaking class of medications, GLP-1 agonists, are revolutionizing the treatment of sleep apnea. In this insightful discussion, Dr. Craig Walker and Terry Roberts delve into the profound impact these drugs can have on addressing the underlying causes of sleep apnea, particularly obesity. Explore the recent approval of Trulicity…

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Conversations from the Heart with Prof Laurence Sperling 28:34

7M ago28:34

28:34

Send us a text Wrap up February with the latest episode of the World Heart Podcast! This time, hosts Lisa Hadeed and Shreya Shrikhande, PhD welcome Prof. Laurence (Larry) Sperling, a leading expert in preventive cardiology, to discuss the critical connection between influenza and heart health. Prof. Sperling shares key insights on how the flu can i…

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Ep. 24 - The Worried well: Navigating Cardiovascular Health Concerns 17:51

8M ago17:51

17:51

Welcome to Cardiovascular Matters! In this episode, Dr. Craig Walker and Terry Roberts tackle an important question: How do you know if you're at risk for heart disease, even if you feel fine? Many people appear to be in perfect health—until they suffer a sudden cardiac event. This leaves loved ones wondering, Could it have been prevented? Dr. Walk…

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Global Heart Perspectives - New Leadership and Visions for Advancing Cardiovascular Research 34:20

8M ago34:20

34:20

Send us a text Kick off 2025 with the Global Heart Podcast! Our January episode features Dr. Raul Santos, Global Heart's new Editor-in-Chief, and Dr. Jagat Narula, WHF President, sharing their inspiring visions for advancing global cardiovascular research through Global Heart and the World Heart Federation to improve heart health worldwide.…

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Ep. 23 - Defeating Obesity: How GLP-1 Medications Change Lives 26:02

9M ago26:02

26:02

Welcome to Episode 23 of Cardiovascular Matters! In this inspiring episode, Terry Roberts shares his incredible journey of losing over 100 pounds in just eight months, thanks to groundbreaking GLP-1 medications and guidance from Dr. Craig Walker, founder of the Cardiovascular Institute of the South. In this episode, you’ll learn: The impact of obes…

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Ep. 22 - The Truth About Statins: Benefits, Risks, and Alternatives 33:21

9M ago33:21

33:21

Welcome to Episode 22 of Cardiovascular Matters! In this engaging discussion, Terry Roberts and Dr. Craig Walker, founder of the Cardiovascular Institute of the South, dive deep into one of the most asked questions about cardiovascular health: statins and cholesterol management. In this episode, Dr. Walker explains: Why statins are a cornerstone of…

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Conversations from the Heart: INTERASPIRE Study with Prof. David Wood 22:27

9M ago22:27

22:27

Send us a text Join us for the latest episode of the World Heart Federation Podcast, hosted by WHF Senior Science Advisor, Pablo Perel. This time, we welcome Professor David Wood, a global leader in cardiovascular prevention, to discuss the groundbreaking and recently published INTERASPIRE study. Discover its key findings related to the critical ga…

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Ep. 21 - Renal Denervation: A Game-Changer in Hypertension Treatment 18:51

10M ago18:51

18:51

In this insightful episode of Cardiovascular Matters, host Terry Roberts and renowned cardiologist Dr. Craig Walker delve into the groundbreaking technology of renal denervation and its profound implications for the treatment of hypertension. High blood pressure, or hypertension, is a major risk factor for a host of cardiovascular complications, in…

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Ep. 20 - Preventing Amputations: The Lifesaving Work of Dr. Craig Walker 18:55

10M ago18:55

18:55

In this powerful episode, host Terry Roberts sits down with Dr. Craig Walker, the founder of Cardiovascular Institute of the South, to discuss his lifelong mission to prevent unnecessary amputations for patients suffering from peripheral vascular disease and critical limb ischemia. Dr. Walker shares how he became deeply committed to this cause, rec…

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Ep. 19 - Conquering High Blood Pressure: Exploring the Potential of Renal Denervation 22:53

11M ago22:53

22:53

In this episode of Cardiovascular Matters, Dr. Craig Walker and Terry Roberts delve into the groundbreaking treatment of renal denervation for patients struggling with uncontrolled hypertension and it has been approved by the FDA. Hypertension is a prevalent and potentially life-threatening condition, often requiring a combination of medications to…

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Ep. 18 - Special Edition: Pioneering Limb Salvage - Dr. Walker's Award-Winning Approach to Peripheral Artery Disease 22:38

12M ago22:38

22:38

In this special edition of the Cardiovascular Matters podcast, host Terry Roberts sits down with Dr. Craig Walker, the founder of the Cardiovascular Institute of the South, to discuss his groundbreaking work in the field of peripheral artery disease (PAD) and limb salvage. Dr. Walker shares his personal journey, the challenges he has faced, and the…

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Ep. 17 - Acute Limb Ischemia: A Medical Emergency Requiring Prompt Intervention 18:15

1y ago18:15

18:15

In this episode of Cardiovascular Matters, we delve into the critical topic of acute limb ischemia, a medical emergency that requires immediate attention. Dr. Walker, a renowned vascular specialist, provides a comprehensive overview of this condition, highlighting the importance of early diagnosis and prompt treatment. Key Points Discussed: Acute l…

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Ep. 16 - Critical Limb Ischemia: Approaches to Treating Critical Limb Ischemia 24:32

1y ago24:32

24:32

In this episode of Cardiovascular Matters, Dr. Craig Walker and Terry Roberts discuss the critical issue of critical limb ischemia (CLI), a severe form of peripheral artery disease. They explore the historical treatment approaches, the evolution of minimally invasive interventions, and the importance of a comprehensive approach to limb salvage. The…

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Ep. 15 - Understanding Peripheral Artery Disease: Causes, Symptoms, and Preventive Measures 20:16

1y ago20:16

20:16

In this episode of Cardiovascular Matters, Dr. Craig Walker and Terry Roberts delve into the critical topic of peripheral artery disease (PAD). They highlight the alarming prevalence of PAD, with an estimated 25 million Americans affected, and emphasize its deadly nature, noting that a person with a new PAD diagnosis is as likely to die of a heart …

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Ep. 14 - Understanding & Managing High Blood Pressure: Men's health Preventative Screening Guide 16:48

1y ago16:48

16:48

In this in-depth podcast, cardiologist Dr. Craig Walker provides a thorough overview of high blood pressure (hypertension) - one of the leading risk factors for heart disease and stroke. Dr. Walker explains what blood pressure is and why it's important to control. He discusses the various causes of high blood pressure, including both primary (essen…

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Ep. 13 - Understanding PCSK9 Inhibitors for Cholesterol-Lowering: Men's health Preventative Screening Guide 12:08

1y ago12:08

12:08

Dr. Craig Walker and Terry Roberts discuss a new class of injectable cholesterol-lowering drugs called PCSK9 inhibitors. These medications provide an additional option for lowering LDL ("bad") cholesterol beyond statin therapy alone. Dr. Walker explains how PCSK9 normally works to block the recycling of LDL receptors in the liver, preventing furthe…

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Ep. 12 - Understanding Cholesterol-Lowering Medications: Men's health Preventative Screening Guide 19:31

1y ago19:31

19:31

Join Dr. Craig Walker as he provides an in-depth look at cholesterol-lowering medications, with a focus on statins. In this informative discussion, Dr. Walker breaks down the science behind these life-saving drugs, explaining how they work to reduce cholesterol production and increase its removal from the body. Learn about the two main types of sta…

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Ep. 11 - Men's health Preventative Screening Guide: Don't Wait for Symptoms!! 33:02

1+ y ago33:02

33:02

In this episode of Cardiovascular Matters, Dr. Craig Walker discusses the importance of regular preventative health screenings for men to assess risk factors and detect early signs of cardiovascular disease. He recommends basic blood tests to check cholesterol levels, inflammation markers, and overall health. Additional tests like calcium scoring o…